Clinical Study on 94 Cases of Primary Cancer of the Liver

A Clinical study on 94 cases of primary liver cancer who were confirmed at Ewha Womans University Hospital from January 1984 to December 1986 was carried out. The result obtained are as follows: 1) The ratio of male to female is 3.9 : 1, and highest incidence rate is 42.6% in 6th decade. 2) The chief complaints are RUQ abdominal pain, epigastric discomfort, dyspepsia, weight loss in the decreasing order. Physical examination shows hepatomegaly, ascites and jaundice. 3) Clonorchis sinensis infestation reveals 8.5% of cases. 4) Liver function tests shows serum globulin elevation in 96.8%, AST(aspartate aminotransferase, SGOT) elevation in 91.5%, alkaline phoaphatese elevation in 86.2%, in order of frequency. 5) Alpha-fetoprotein is positive (>400ng/ml) in 72.3% of cases. 6) Serum HBsAg is positive in 75.0% of cases. 7) Alpha-fetoprotein is apt to be positive in the HBsAg positive cases. 8) Space occupying lesions are demonatrated by liver scanning in 93.6% of cases: 73.9% in the right lobe, 11.4% in the left lobe and 14.7% in the both lobes. 9) Twelve (70.6%) of cases are assoiated with cirrhosis of liver. Of cases 75.0% is macronodular.