Study on the Definitive Radiation Therapy for Carcinoma of the Uterine Cercix
Published Online: Jul 24, 2015
Abstract
Ninety five patients with carcinoma of the uterine cervix was treated with definitive radiation therapy at Ewha Womans University Hospital from March 1982 through December 1985. Minimum 3-year follow-up was done.
According to FIGO stage. there were 15 (15.8%), 20 (21.0%), 32 (33.7%), 11 (11.6%), and 17 cases (17.9%) of stages IB, IIA, IIB, IIIA, and IIIB, respectively. A combination of teletherapy by Linear accelerator 6MV and intracavitary radiotherapy with Cs-137 using Fletcher-suit applicator was done in all patients. Radiation doses to point A (paracervical area) and B (obturator node) were 80-90 Gy and 50-60 Gy, respectively in stages I-IIA and somewhat higher in stages IIB-IIIB.
The local control rates were 100, 85.0, 78.1, 63.6, and 58.8% in stages IB, IIA, IIIB, IIIA and IIIB, respectively. The most common failure site was pelvis (65.2%): six patients had locoregional failure with distant metastasis and two had only distant metastasis. Seven patients developed complications four had hematuria, two had rectal bleeding. and one had vesicovaginal fistula. Most of complications were developed between 2 and 3 years after completion of radiotherapy. Three-year survival rates were 100, 82.4, 78.1, 63.6, and 52.9% in stages IB. IIA. IIB. IIIA and IIIB. respectively.
