A Case of Granular Cell Tumor

Granular cell tumor(GCT) is an uncommon tumor characterized clinically by an asymptomatic, solitary nodule in the tongue and skin, especially head and neck region. Histopathologically the broad fascicles of tumor cells infiltrate the dermis and the tumor cells are characterized by plump cells with faint eosinophilic, granular cytoplasm.

The origin of cells has been debated for decades. However electron microscopic and immunohistochemical studies strongly support a Schwann cell origin.

We report a case of granular cell tumor arising from the anterior chest of 12-year-old healthy girl, which exhibited the distinctive histopathologic appearance and also reactive with PAS, S-100, and NSE.