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The Ewha Medical Journal
Ewha Womans University School of Medicine

Ewha Med J 1978; 1(4):283-287

pISSN: 1598-7450

DOI: https://doi.org/10.12771/emj.1978.1.4.283

Original Article

An Experimental Study about the Effect of Local Anesthesia on Skin Flap Survival

Han Joong Kim
Corresponding author: Han Joong Kim. Department of Plastic Surgery, College of Medicine, Ewha Womans University, Korea.

Copyright ⓒ 1978. Ewha Womans University School of Medicine. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: Jul 24, 2015

Abstract

Despite the wide use of local anesthetics in surgery, relatively little has been proven about the effects of these agents on skin flaps. The following investigation was undertaken to study the influence of local anesthetic agents, which and without epineprine, on the survival of skin flaps in the rabbits. Infiltration with xylocaine or procaine alone had no influence on the viability of either nondelayed or delayed flaps. However, the addition of 1:100,000 epinephrine, which was not detrimental to survival length in nondelayed flaps, significantly reduced the surviving length in delayed skin flaps.