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The Ewha Medical Journal
Ewha Womans University School of Medicine

Ewha Med J 1993; 16(4):389-393

pISSN: 1598-7450

DOI: https://doi.org/10.12771/emj.1993.16.4.389

Original Article

The Study of Hepatitis C Virus Antibody Positive Liver Disease

Ki Sook Hong

Copyright ⓒ 1993. Ewha Womans University School of Medicine. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: Jul 24, 2015

Abstract

Presented study was conducted to determine that the hepatitis C virus(HCV) may play a role in the pathogenesis of chronic liver disease including hepatocellular carcinima and liver cirrbosis.

Using 2nd generation EIA author examined serum anti-HCV in total 2,641 cases, including liver disease, physical check-up subjects at EWHA Womans University Hospital during 1 year of 1992.

The results were as fo11ows : Among total 2,641 patients, overall prevalence of anti-HCV was 4.5%, 1.7% positive rate for subjects whose physical check-up. Among total 103 anti-HCV positive patients, the majority was chronic liver disease, liver cirrhosis, and hepatoma. The positivity of HBs Ag in anti-HCV positive patients was 4.4% and the anti-HBc was 49.5%. The mean ALT level was 69.3 U/L and the abnormal high level was found in 57.3% in anti-HCV positive patients.

On the basis of the results above, anti-HCV test is very useful for the diagnosis and management in not only chronic liver disease such as hepatocellular carcinoma and cirrhosis, but also chronic hepatitis diagnosed as B-hepatitis.