A Case of Selective IgA Deficiency Associated with Scleroderma

Ki Sook Hong, Soon Nam Lee*, Jeong Hee Hahm**

Copyright ⓒ 1993. Ewha Womans University School of Medicine. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: Jul 24, 2015

Abstract

Selective absence of serum IgA is the most commonly diagnosed form of human immnndeficiency disease, being reported in about one in 500-700 subjects in population surverys. Datailed clinical and laborattory studies of subjects with selective IgA deficiency generally reveal significantly increased incidence of sinopulmonary infection, gastrointestinal symptomatology, autoimmune disease and autoantibodies.

Authors experienced selective IgA deficiency associated with an scleroderma in a 25 years old young woman. She had pulmonary tuberculosis, high IgE level, reactive rheumatoid factor, positive for antinuclear antibody, and no presence of anti-IgA antibody.