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The Ewha Medical Journal
Ewha Womans University School of Medicine

Ewha Med J 1996; 19(1):31-36

pISSN: 1598-7450

DOI: https://doi.org/10.12771/emj.1996.19.1.31

Case Report

A Case of Huge Retroperitoneal Hematoma in Chronic Myelogenous Leukemia

Ki-Ryung Park, Young-Sun kim, Sa-Young Park, Jin-Hyuk Choi, Soon-Nam Lee, Hwa-Soon Chung*

Copyright ⓒ 1996. Ewha Womans University School of Medicine. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: Jul 24, 2015

Abstract

Thrombohemorrhagic complications in chronic myeloproliferative disease(CMPD) including chronic myelogenous leukemia(CML) are not rare. Lower incidence of disordered hemostasis is reported in CML compared with other CMPD. The mechanism of thrombohemorrhagic complications might be a consequence of qualitative platelet abnormalites and prolonged bleeding time rather than that of thrombocytosis. Although defect of platelet function has been extensively investigated, there was no established consistent correlation between clinical bleeding and number and function of platelet. The most common site of bleeding complications in the CMPD is superficial mucosa. Bleeding in deep tissue and viscera is very unusual. We report a case of CML which developed a huge spontaneous retroperitoneal hematoma.

Keywords: Thrombohemorrhagic complications; Chronic myelogenous leukemia; Number and function of platelet; Retroperitoneal hematoma