The Ewha Medical Journal
Ewha Womans University School of Medicine
Original Article

Renal Cell Carcinoma Associated with Paraneoplastic Symdrome Mimicking Pyelonephritis

Min Cheol Han, Jae Hun Kim, Sung Jae Park, Dong Won Byun, Duk Hee Kang*, Bong Suk Shim

Copyright ⓒ 2004. Ewha Womans University School of Medicine. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: Sep 30, 2004

Abstract

Renal cell carcinoma can presents wide range of signs and symptoms, and commonly associated with paraneoplastic syndrome. Paraneoplastic manifestations are present in up to 20% of patients with renal cell carcinoma. There is convincing evidence that renal cell carcinoma tumor cells elaborate proteins that serve as mediators of endocrine (ex ; ectopic production of parathyroid hormone-related protein or erythropoietin) as well as nonendocrine paraneoplastic syndromes. A paraneoplastic syndrome may be the various clinical presentation of renal cell carcinoma in a significant number of patients, therefore mimicked other general disease. We report a case of renal cell carcinoma associated with paraneoplastic syndrome mimicking pyelonephritis.

Keywords: Renal cell carcinoma; Paraneoplastic syndrome; Pyelonephritis