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The Ewha Medical Journal
Ewha Womans University School of Medicine

Ewha Med J 1980; 3(3):101-111

pISSN: 1598-7450

DOI: https://doi.org/10.12771/emj.1980.3.3.101

Original Article

The Chemotherapy of Malignant Bone Tumors

Ki Hong Choi, Chung Nam Kang, Jin Man Wang, Young Sung Park
Corresponding author: Young Sung, Park. Department of Orthopaedic Surgery, College of Medicine, Ewha Womans University, Korea.

Copyright ⓒ 1980. Ewha Womans University School of Medicine. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: Jul 24, 2015

Abstract

Experiences in the adjuvant chemotherapy with adriamycin on two cases of osteogenic sarcoma of the femur and tibia and one case of Ewing's sarcoma of the femur are presented.

The two cases of the osteogenic sarcoma were treated by a combination of radical amputation and chemotherapy.

One case of the Ewing's sarcoma was treated by the megavoltage radiotherapy and chemotherapy.

One patient with the osteosarcoma died of late pulmonary metastasis 13 months after the diagnosis and treatment, however, this patient had discontinued hie chemotherapy in three months. And also his initial amputation was delayed four months from initial diagnosis because of his hesitation.

Other two cases of osteogenic and Ewing's sarcoma are carrying on normal active daily life without local recurrance or pulmonary metastasis 11-17 months after the diagnosis of the osteogenic and Ewing's sarcoma respectively.

The observation and follow up period of our cases are too short to permit definite conclusions. However, preliminary results and the review of the literatures strongly support the possibility that adjuvant chemotherapy has improved the prognosis of the patients with the malignant bone tumors.