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The Ewha Medical Journal
Ewha Womans University School of Medicine

Ewha Med J 1983; 6(1):23-27

pISSN: 1598-7450

DOI: https://doi.org/10.12771/emj.1983.6.1.23

Original Article

A Comparative Study on the Clinical Effects of Various Topical Corticosteroids by Psoriasis Plaque Test

Jin Kwon Kim, Ki Bum Myung, Hong Il Kook
Corresponding author: Hong Il Kook. Department of Dermatology, College of Medicine, Ewha Womans University, Korea.

Copyright ⓒ 1983. Ewha Womans University School of Medicine. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: Jul 24, 2015

Abstract

The psoriasis plaque test, as a clinical and non-artificial model, provides information on the antiproliferative effect of topical corticosteroids, and it makes possible to ealuate various preparations simultaneously at a given time. In this assay we compared the antiproliferative effects of six topical corticosteroids with occlusive dressing technique in fourteen psoriatic patients. The results are summerized as follows : 1) The psoriasis plaque test was an adequate method for evaluating antiproliferative effects of various corticosteroid preparations. 2) In contrast to prednisolone and triamcinolone acetonide, the effects of desoxymethasone, halcinonide, fluocinide, triamcinolone benetonide were evident, and the best of all was desoxymethasone. 3) No side effect developed during test period.