Biochemical and Clinical Studies for the Urolithiasis

Urolithiasis is the most important disease and one of the most common diseases in the fields of Urology, and recently the incidence of urolithiasis has increasing tendency with the improvement of living condition in Korea. Though the cause of urolitiasis has not clearly yet, it has been beleived that diet with food containing rich calcium, phosphate, oxalate and uric acid components plays a great role in the stone formation. Prevously the author had clarified the relationship between urolithiasis and diversified and westernized food life with milk and diary products in Koresn people. Accurate analysis of urinary calculi is fundamental for study of the etiology of stone formation and essential for treatment and prevention of urolithiasis. In this article, by the biochemical method the author had analyzed 100 urinary calculi randomly selected among calculi which were obtained from the patients with urolithiasis during the past 8 years and 7 months from April, 1976 to October, 1984, and made a study of 593 patients with urolithiasis who were admitted to our department of Urology in the same period with retrospective statistical analysis by computer. The following results were obtained. 1) The result of biochemical analysis of 100 urinary calculi revealed multiple composition in all cases and the most part of calculi(73%) were composed with calcium, magnesium, phosphate, oxalate, xantine, and uric acid. Calcium component containing calculi were 97% and only organic component containing calculi were 1%