The Ewha Medical Journal
Ewha Womans University School of Medicine
Original Article

The Histopathologic Observation of Necrotizing Lymphadenitis

Woon Sup Han
Corresponding author: Woon Sup Han. Department of Pathology, College of Medicine, Ewha Womans University, Korea.

Copyright ⓒ 1984. Ewha Womans University School of Medicine. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: Jul 24, 2015

Abstract

Since 1972, the necrotizing lymphadenitis, histiocytic necrotizing lymphadenitis without granulocytic infiltration etc. Seven cases of necrotizing lymphadenitis has presented in this study. Most of them were young men characterized by persistent lymphadenopathy with or without fever. The histopathologic features of lymphnodes showed focal or diffuse well circumscribed paracortical necrotizing lesion, abundant karyorrhectic debris and aggregates of large mononuclear cells. However, there were no infiltrates of plasma cells and neutrophils. The remaining areas of lymphnodes showed severe degree of paracortical hyperplasia without significant hyperplasia of lymphoid follicles in the cortex.