Study on the Hematologic and Blood Chemical Tests in Preelcampsia

The purpose of this study was to determine if differences could be found in hematologic and blood chemical assays of women with preeclampsia compared with normal pregnant controls. Seventy patients with severe preeclampsia, seventy with preeclampsia, and ninety normal pregnant women for control were taken part in this study at the Department of Obstetrics and Gynecology, Ewha Womans University Hospital from January, 1984 to March, 1986. The levels of hemoglobin, hematocrit, total bilirubin, alkaline phosphatase, serum glutamic oxaloacetic transaminase(SGOT), serum glutamic pyruvic transaminase(SGPT), total protein, albumin, blood urea nitrogen(BUN), creatinine, and uric acid in both of mild preeclampsia and severe preeclampsia group were measured and compared with those of normal pregnancy group. The results of this study were summarized as follows:1) The mean levels of hemoglobin, hematocrit, and platelets in both of mild preeclampsia and severe preeclampsia group were not significantly different from those of normal pregnancy group. 2) The mean total bilirubin levels in both of mild preeclampsia and severe preeclampsia group were not significantly different from that of normal pregnancy group. The mean level of alkaline phosphatase of mild preeclampsia group was significantly lower than of normal pregnancy group, but that of severe preeclampsia group was not significantly lower than that of normal pregnancy group. The mean SGOT level of mild preeclampsia group was not significantly higher than that of normal pregnancy group, but that of severe preeclampsia group was significantly higher than that of normal pregnancy group. The mean SGPT levels in both of mild preeclampsia and severe preeclampsia group were significantly increased than of normal pregnancy group. 3) The mean total protein levels in both of mild preeclampsia and severe preeclampsia group were significantly lower than that of normal pregnacy group. The mean serum albumin levels in both of mild preeclampsia and severe preeclampsia group were also significantly lower than of normal pregnancy group. The mean total protein and serum albumin level of sever preeclampsia group were significantly lower than those of mild preeclampsia group. 4) The mean BUN and serum creatinine level in both of mild preeclampsia and severe preeclampsia group were significantly higher than those of normal pregnancy group. The mean serum uric acid level of severe preeclampsia group was significantly increased than that of mild preeclampsia group.