| Mandard | | CR, no viable cancer cells, fibrosis extending through the different layers of the wall | Rare residual cancer cells scattered through the fibrosis | Increased number of residual cancer cells, fibrosis predominates | Residual cancer outgrowing fibrosis | Absence of regressive changes |
| Dworak | No response | Minimal response (dominant tumor mass with obvious fibrosis, vasculopathy); fibrosis <25% of tumor mass | Moderate response (dominant fibrotic changes with a few easy-to-find tumor cells in groups); fibrosis 25%–50% of tumor mass | Near CR (few microscopically difficult-to-find tumor cells in fibrotic tissue with or without mucous substance); fibrosis >50% of tumor mass | CR (no tumor cells, only fibrotic mass or acellular mucin pools) | |
| Ryan/AJCC | CR, no viable cancer cells | Near-CR, single cells, or rare small groups of cancer cells | Partial response, residual cancer with evident tumor regression but more than single cells or rare small group of cancer cells | Poor or no response, extensive residual cancer with no evident tumor regression | | |
| MSKCC | | 100% tumor response | 86%–99% tumor response | ≤85% tumor response | | |