Table 3. List of 16 articles on the health of gender minorities

No Year Authors Primary exposure or measure Outcome assessment Sample design Sample characteristics Significant main effect association indicating adverse health effects of LGB
1 2006 Kim et al. [39] Gender identity (TGD) Psychological burdens (BDI, SADS, SES, FACES-III) Offline survey TGD, N=43, 49 matched non-transsexual High depression burden, social avoidance and distress, low self-esteem scale, family adaptability and cohesion.
2 2018 Lee et al. [50] Experiences of and barriers to transition-related healthcare Gender affirming care RCP2* online survey TGD, N=278 Barrier: cost, negative experiences in healthcare settings, lack of specialized healthcare professionals and facilities, and social stigma against TGD.
3 2019 Lim et al. [41] Demographics Gender identity-related characteristics Hospital medical record review TGD, N=54 20% had mental disorder other than gender dysphoria.
4 2020 Lee et al. [44] Internalized transphobia Depressive symptoms, suicidal ideation, and suicide attempts. RCP2 online survey TGD, N=207 Depressive symptom, suicidal ideation and attempts.
5 2020 Lee et al. [40] Gender identity (TGD) Physical health, mental health RCP2 online survey TGD, N=255 Depressive symptom, suicidal ideation.
6 2021 Yun et al. [52] Cross-sex hormone Body composition, bone mineral density, muscle strength Hospital medical record review TGD women, N=11 Increase fat mass, decrease in overall lean body mass and handgrip strength.
7 2021 Lee et al. [46] Public Bathroom-Related Stressors Depressive Symptoms RCP3 online survey TGD, N=557 Depressive symptoms.
8 2022 Lee et al. [43] Discrimination due to TGD identity Healthcare avoidance and delay RCP2 online survey TGD, N=244 Healthcare avoidance and delay.
9 2022 Eom et al. [49] Discrimination due to TGD identity Sleep problems RCP3 online survey TGD, N=583 Sleep problems.
10 2022 Choo et al. [34] Discrimination due to TGD identity Dymptoms of depression and anxiety RCP2 online survey TGD, N=269 Depressive and anxiety symptoms.
11 2023 Lee et al. [45] Gender identity change effort Depression, PTSD, suicide attempts RCP3 online survey TGD, N=566 11.5% Gender identity change effort experience, more depression, panic disorder, suicide attempt.
12 2023 Lee et al. [71] Transgender-specific COVID-19-related stressors Past-week depressive symptoms RCP3 online survey TGD, N=564 30% TGD-specific COVID-19 related stressor experience and more depressive symptoms. Barrier to gender affirming care: economic hardship, limited access to hospital.
13 2023 Kim et al. [42] Discrimination due to TGD identity Healthcare avoidance and delay RCP2 online survey TGD, N=190 53.7% experienced anti-transgender discrimination at initial and one year follow up survey, and they experienced more non-transition-related healthcare avoidance and delay.
14 2023 Kim et al. [53] Demographics Gender identity disorder, intersex Administrative data (HIRA) TGD, N=8,602 For 15 years (2007-2021), 8,602 people who received the F64 codes (gender identity disorder), 45 people diagnosed intersex.
15 2024 Eom et al. [48] Situational avoidance Mental health (1week depression, 2week anxiety) RCP2 online survey TGD, N=268 50.4% experienced avoided daily activities (public bathroom use, job application, and hospital visit) and more anxiety symptom.
16 2024 Oh et al. [51] Demographics Onset of gender incongruence Hospital medical record review TGD, N=337 Mean age of onset of GI was 10.6 years (29% before age 6, 61% before age 12, and 87% before age 15), TGD lived with GI for almost 14 years before gender affirming hormone therapy.
RCP2 online survey: rainbow connection project 2.
RCP3 online survey: rainbow connection project 3.
TGD, transgender and gender diverse; BDI, Beck's Depression Inventory; SADS, Social Avoidance and Distress Scale; SES, Self-Esteem Scale; FACES, Family Adaptability and Cohesion Evaluation Scale; PTSD, post-traumatic stress disorder; COVID-19, coronavirus disease-19; HIRA, Health Insurance Review and Assessment Service.