Example 2 Table. Sensitivity of the Rate Ratio for Cardiovascular Outcome to an Unmeasured Confounder

Prevalence of Unmeasured Binary Confounder in the Exposed Group, % Prevalence of Unmeasured Binary Confounder in the Comparator Group, % Unmeasured Binary Confounder Rate Ratio High Exposure Rate Ratio (95% Cl)*
90 10 1.5 1.20 (1.01-1.42)
90 50 1.5 1.43 (1.22-1.67)
50 10 1.5 1.39 (1.18-1.63)
90 10 2 0.96 (0.81-1.13)
90 50 2 1.27 (1.11-1.45)
50 10 2 1.21 (1.03-1.42)
90 50 3 1.18 (1.01-1.38)
50 10 3 0.99 (0.85-1.16)
90 50 5 1.08 (0.85-1.26)
Cl, confidence interval.
Adjusted for age, sex, cardiovascular drug use, and unmeasured binary confounder.
Table adapted from Wei et al. [184].