3 Cases of Chronic Myelocytic Leukemia in Children

Nan Kyu Lim, Young Chin Chung, Chul Kyu Kim, Kyoung Sook Han, Byoung Soo Kim

Corresponding author: Byoung Soo Kim. Department of Pediatrics, College of Medicine, Yonsei University

Copyright ⓒ 1978. Ewha Womans University School of Medicine. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published Online: Jul 24, 2015

Abstract

3 cases of chronic Myelocytic Leukemia in children were seen during 5 year period 1973~1978. They were 6 year old male, 10 year old male and 12 year old female. On physical examination, pallor and splenomegaly were noted with nontender, hard and enlarged lymph nodes in the neck, axilla and inguinal region. They presented with a leukocytosis 100,000 per cumm~150,000 per cumm. The Philadelphia chromosomes were not detected. They in the chronic phase of chronic myelocytic leukemia responded well to busulfan. Maintenance of the hematologic remission has been possible with small daily doses of busufan.