Mixed Mesodermal Tumor of the Ovary: One Case Report
Published Online: Jul 24, 2015
Abstract
Mixed mesodermal tumor and carcinosarcoma are well recognized disease entities in the uterus. It is not widely known, however, that histologically identical tumors also occur in the ovary. Most patients were reported postmenopausal and iparous. An enlarging abdomen with a palpable mass was the most common clinical presentation. Though grossly carcinosarcoma and mixed mesodermal tumors are usually indistinguishable, mixed mesodermal tumors contain heterologous components, such as striated muscle cells, cartilage, osteoid and fat, as well as carcinosarcoma. The disease is usually advanced when diagnosed and provides bad prognosis.
A case of mixed mesodermal tumor of the ovary is presented. The patient was 62 years old postmenopausal woman and the numbers of parity and delivery were twice without an experience of abortion. Though abdominal mass was incidentally detected one year ago, newly found diabetes mellitus postponed the operation. These days it has rapidly grown up to child head size accompanied with abdominal pain, and right salpingoophorectomy was done, which measured about 15cm in maximum dimension and 1,000gm in weight. The tumor is largely cystic remaining peripheral red brown to grey white solid part. Histologic findings are characterized by papillary, well differentiated and undifferentiated carcinoma, and spindle cell sarcoma merged with myxoid and chondroid islands. The cartilage is pleomorphic add anaplastic.