A proposal on Cosmetic Safly Test: The Second Paper The Experimental Study on Comedogenecity of Cosmetics

This present study was performed to evaluate the comedogenicity of several cosmetics. The test materials were applied to one ear canal of three rabbits daily for 6 weekdays for 2 weeks.

The results were as follow :

1) Among the 14 cosmetics, extremely weak comedogenicity was shown in one cosmetic, mild comedogenicity in 10 cosmetics and moderate comedogenicity in 3 cosmetics.

2) There were no significant differences of comedogenicity among cosmetic species.

3) The rabbit ear assay was a rapid, effective screening test for evaluation of comedogenicity of cosmetics.