Correlation with Sonographic and Pathologic Findings of Fibrocystic Disease of the Breast

To evaluate pathologic findings of fibrocystic disease correlated with sonographic findings in the patients with solid lesion on ultrasonography.

Total 63 pathologically proven fibrocystic disease in 57 patients are retrospectively evaluated. On ultrasonography, the lesions were divided into solid and non-solid mass-like lesions. We analyzed the margin and echogenicity of solid mass-like lesions that were correlated with pathologic findings and also statistically analyzed Chi-square and Fisher's exact test.

Ultrasonogram of fibrocystic disease showed solid mass-like lesion in 73% and non solid mass-like lesion in 27%. Among the solid lesions, well-defined margin revealed in 72%, ill-defined margin in 28% and hypoechoic in 59%, isoechoic 41%. On the pathologic analysis, the solid and the non-solid mass-like lesion showed respectively : fibrous stroma in 56.5% and 53%, fibroadenomatous change in 50% and 12%, mixed stroma in 41% and 35.3%, cystic change in 37% and 70.6%, ductectasia in 28% and 58.8%, lobular hyperplasia in 26% and 12%, ductal hyperplasia 13% and 5.9%, and adenosis in 8.7% and 0%. The solid lesions showed more fibroadenomatous change and the difference between there was statistically significant(p=0.008).

The solid mass-like lesion, which represented as a well-defined isoechoic benign mass on ultrasonogram was more common than as expected, and this was due to the fibroadenomaous change on histopathology.