A Study on the Lipid Metabolism and Hemoglobin A1c in Diabetes Mellitus Patients

The authors studied 50 controls(25 male and 25 female) and 79 diabetes mellitus patients(38 male and 41 female) who were admitted to Ewha Womans University Hospital from June, 1983 to May, 1984 to investigate the disorders of lipid metabolism, hemoglobin A_1c and their correlaton. The results were as follows: 1) Age incidence was highest in the 6th decades. 2) Mean fasting blood sugar was 191.9±82.29mg% and postprandial 2hour blood sugar was 278.81±118.19mg% in male diabetes mellitus patients, and 196.48±68.94mg% and 261.16±85.84mg% in female diabetes mellitus patients. After control diabetes mellitus blood sugar levels were decreased significantly. 3) Hemoglobin A_1clevels at fasting and postprandial 2 hour were significantly higher than those of controls. And Hemoglobin A_1c level were progressivly decreased after 3 months' controlling of diabetes mellitus. 4) Pre-β and β-lipoprotein, triglycerides and cholesterol were significantly higher than those of controls but α-lipoprotein was lower than that of controls. After 6 months of diabetic control, pre β-lipoprotein, triglycerides and cholesterol were decreased. 5) Between Hemoglobin A_1c and fasting blodo sugar had positive correlation, an cholesterol and hemoglobin A_1c also had positive correlation, but those were not statistically significant.