A case of di Guglielmo syndrome in 9 year old boy was presented. This syndrome is characterized by excessive erythroid precursors with abnormal morphology both in the bone marrow and blood, and rare in childhood. He visited with the chief complaints of general weakness, weight loss, epistaxis and abdominal distension. Physical examination showed pallor, grade I-II/VI systolic murmur on apical area and marked abdominal distension with hepatosplenomegaly. we confirmed the patient by the peripheral smear and bone marrow aspiration.

3 cases of chronic Myelocytic Leukemia in children were seen during 5 year period 1973~1978. They were 6 year old male, 10 year old male and 12 year old female. On physical examination, pallor and splenomegaly were noted with nontender, hard and enlarged lymph nodes in the neck, axilla and inguinal region. They presented with a leukocytosis 100,000 per cumm~150,000 per cumm. The Philadelphia chromosomes were not detected. They in the chronic phase of chronic myelocytic leukemia responded well to busulfan. Maintenance of the hematologic remission has been possible with small daily doses of busufan.

We reviewed the records of prematurity and birth weight infants who had been delivered at Ewha Womans University Hospital from Jan. 1975 to Dec. 1977. The results were as follows: 1) The incidence of prematurity and low birth weight infants were 53.6 and 77.3 per 1,000 newborns. 2) In delivery type, normal vaginal delivery was more frequent in prematurity and low vith weight infants than normal mature infants and c/section was less frequent. 3) The incidence of prematurity and low birth weight infants was more frequent in multiparity. 4) In the etiologic diseases of mother during pregnancy of prematurity and low birth weight infants, spontaneous premature rupture of membrane was first. 5) Initial weight loss was more prolonged and weight was regained slowly in low birth weight infants. 6) The neonatal mortality rate of prematurity and low birth weight infants was 92.5 per 1,000 prematurity and low birth weight infants and was decreased recently. 7) The relation between neonatal mortality rate and birth weight, neonatal mortality rate and gestational periods, neonatal mortality rate and Apgar score were significant. But the relation between mortality rate maternal age was not signigicant. 8) In etiology of neonatal death in prematurity and low birth weight infants, respiratory distress syndrome was first.

An analysis present of 96 cases of the acute febrile convulsions in Korean children, treated at the pediatric ward, Ewha Womans University Hospital from Jan 1, 1968 to Dec. 31, 1976. The average number of the patients in the annual incidence was 10 cases, which was 1.9 percent of the total admitted patients of the pediatrics in our hospital. Seasonal distribution revealed as the highest in summer (31.3%) and fifty-eight, 60.4 percent of the patients were male and 38 or 39.6%, female. The highest portion of those with febrile seizures, namely 27.1%, occured in the 1 to 2 years of age, followed by 18.8% in the first year of life and 15.7% in the 3~4 years of life. The family history in siblings, parents and/or near relatives showed convulsions in 16 cases(16.7 percent). The risk of seizure in the acute febrile convulsions increased with the temperature. In 44.8% of the author's cases the temperature was 38°~39°9'C. But we also experienced the convulsive children (10.4%) whose temperatures were in mild degree (under the 38℃). Infections and fever are partners in crime. In the 96 cases, 65.7% involved acute upper respiratory infection. The others were gastroenteritis (13.4%)m pneumonia (11.6%), bronchitis (2.1%) in orders. Tonic and clonic convulsions were found in 83 cases (86.5%) and the other was twitching (14.5%). In routine hematologic findings anemia was present in 26 cases(37.1%) and the normal value of hemoglobin was in 70 cases(72.9%). Leukocytosis (>10,000/mm³) included in 60 cases (60.5%). We found that hyponatremia was a common finding in children admitted to our hospital with febrile convulsion. The mean Na was 135 mEq/L and hyponatremia was present in 6 cases (31.6%) of the 19 cases. The highest incidence in the duration of seizure was represented in those lasted 5 to 30 minutes as 36 cases (37.6%). In author's study 94.8% of the 96 cases had but one febrile seizure and the recurrence attack represented only 5.2%. The mean hospital day was 2.5 days.

Author reviewed the experience with 50 cases seen at the Ewha Womans University Hospital in Seoul between January 1967 and December 1977, with an overal mortality of 50.0% from the disease. The average number of patients in the annual incidence was 4~5 cases, which was 0.8% of the total admitted patients of pediatrics in our hospital. Monthly distribution revealed as the highest in summer (42.0%) and the male to female ratio was 3.2:1. Compared with Seoul and the rural area of its outbreak, there was a significantly higher in Seoul (82.0%) than in the rural area(18.0%). Neonatal tetanus was a serious problem in some areas of our country where modern aseptic techniques were not employed. And the umbilical contamination by the dirty scissor was the highest source of infection (66.0%). Seventy-two percent of 50 cases was delivered in the contaminated environment. The incubation period was extremely variable but the usual range was 5 to 7 days(36cases). A short incubation (less than 10 days) was associated with a higher mortality rate (55.6%) than the incubation period over than 10 days with a mortality of 14.3%. The most common chief complaint on admission was the stop sucking (86.0%). The others were convulsion(62.0%), trismus (32.0%), fever (30.0%), irritability(18.0%), spasticity(16.0%) in orders. There was a significant correlation between fever and the outcome. The cases who were mild degree in the temperature(37°~37°9'C) had a better chance of recovery (62.5%). The mean hospital day in the improved cases was 21 days. The percentage of the beginning of the sucking ability within 1 to 2 weeks after the onset of the disease was high as 56.0%. The sucking power was normalized within the 4 weeks after the onset of the desease in all of the improved cases.