• Contact us
  • E-Submission
ABOUT
BROWSE ARTICLES
JOURNAL POLICIES
FOR CONTRIBUTORS

Page Path

  • HOME
  • Browse articles
  • Funded articles
4
results for

Funded articles

Filter

Funded articles

Article category

Keywords

Publication year

Authors

Funded articles

Review

[English]
Bridging science and policy in tuberculosis treatment through innovations in precision medicine, drug development, and cohort research: a narrative review
Jinsoo Min, Bruno B. Andrade, Ju Sang Kim, Yoolwon Jeong
Ewha Med J 2025;48(2):e22.   Published online April 2, 2025
DOI: https://doi.org/10.12771/emj.2025.00115
Funded: Korea National Institute of Health
Recent advancements in tuberculosis treatment research emphasize innovative strategies that enhance treatment efficacy, reduce adverse effects, and adhere to patient-centered care principles. As tuberculosis remains a significant global health challenge, integrating new and repurposed drugs presents promising avenues for more effective management, particularly against drug-resistant strains. Recently, the spectrum concept in tuberculosis infection and disease has emerged, underscoring the need for research aimed at developing treatment plans specific to each stage of the disease. The application of precision medicine to tailor treatments to individual patient profiles is crucial for addressing the diverse and complex nature of tuberculosis infections. Such personalized approaches are essential for optimizing therapeutic outcomes and improving patient adherence—both of which are vital for global tuberculosis eradication efforts. The role of tuberculosis cohort studies is also emphasized, as they provide critical data to support the development of these tailored treatment plans and deepen our understanding of disease progression and treatment response. To advance these innovations, a robust tuberculosis policy framework is required to foster the integration of research findings into practice, ensuring that treatment innovations are effectively translated into improved health outcomes worldwide.

Citations

Citations to this article as recorded by  
  • Recent advances in pulmonary tuberculosis, the application of deep learning to medical topics, and highlights from this issue of Ewha Medical Journal
    Hae-Sun Chung
    Ewha Medical Journal.2025; 48(2): e16.     CrossRef
  • 615 View
  • 44 Download
  • 1 Crossref

Original articles

[English]
Development of automatic organ segmentation based on positron-emission tomography analysis system using Swin UNETR in breast cancer patients in Korea
Dong Hyeok Choi, Joonil Hwang, Hai-Jeon Yoon, So Hyun Ahn
Ewha Med J 2025;48(2):e30.   Published online April 2, 2025
DOI: https://doi.org/10.12771/emj.2025.00094
Funded: National Research Foundation of Korea, National Research Foundation of Korea
Purpose
The standardized uptake value (SUV) is a key quantitative index in nuclear medicine imaging; however, variations in region‐of‐interest (ROI) determination exist across institutions. This study aims to standardize SUV evaluation by introducing a deep learning‐based quantitative analysis method that enhances diagnostic and prognostic accuracy.
Methods
We used the Swin UNETR model to automatically segment key organs (breast, liver, spleen, and bone marrow) critical for breast cancer prognosis. Tumor segmentation was performed iteratively based on predefined SUV thresholds, and prognostic information was extracted from the liver, spleen, and bone marrow (reticuloendothelial system). The artificial intelligence training process employed 3 datasets: a test dataset (40 patients), a validation dataset (10 patients), and an independent test dataset (10 patients). To validate our approach, we compared the SUV values obtained using our method with those produced by commercial software.
Results
In a dataset of 10 patients, our method achieved an auto‐segmentation accuracy of 0.9311 for all target organs. Comparison of maximum SUV and mean SUV values from our automated segmentation with those from traditional single‐ROI methods revealed differences of 0.19 and 0.16, respectively, demonstrating improved reliability and accuracy in whole‐organ SUV analysis.
Conclusion
This study successfully standardized SUV calculation in nuclear medicine imaging through deep learning‐based automated organ segmentation and SUV analysis, significantly enhancing accuracy in predicting breast cancer prognosis.
  • 297 View
  • 26 Download
[English]
Status of human rights violations and trauma among North Korean defectors: a cross-sectional study
So Hee Lee, Won Woong Lee, Haewoo Lee, Jin Yong Jun, Jin-Won Noh
Ewha Med J 2025;48(2):e28.   Published online April 10, 2025
DOI: https://doi.org/10.12771/emj.2025.00367
Funded: National Human Rights Commission of Korea
Purpose
This study aimed to identify the types of human rights violations and the associated psychological trauma experienced by North Korean defectors. It also examined the impact of trauma on the defectors’ interpersonal relationships, employment, and overall quality of life, while evaluating existing psychological support policies to suggest potential improvements.
Methods
A multidisciplinary research team conducted an observational survey and in-depth interviews with approximately 300 North Korean defectors residing in South Korea from June to September 2017. Standardized measurement tools, including the Post-Traumatic Stress Disorder (PTSD) Checklist (PCL-5), Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder Scale-7 (GAD-7), and Short Form-8 Health Survey (SF-8), were employed. Statistical analyses consisted of frequency analysis, cross-tabulation, factor analysis, and logistic regression.
Results
The findings revealed a high prevalence of human rights violations, such as public executions (82%), forced self-criticism (82.3%), and severe starvation or illness (62.7%). Additionally, there were elevated rates of PTSD (56%), severe depression (28.3%), anxiety (25%), and insomnia (23.3%). Defectors who resided in China before entering South Korea reported significantly worse mental health outcomes and a lower quality of life. Moreover, trauma was strongly and negatively correlated with social adjustment, interpersonal relationships, employment stability, and overall well-being.
Conclusion
An urgent revision of existing policies is needed to incorporate specialized, trauma-informed care infrastructures within medical institutions. Furthermore, broad societal education to reduce stigma and enhance integration efforts is essential to effectively support the psychological well-being and social integration of North Korean defectors.

Citations

Citations to this article as recorded by  
  • Recent advances in pulmonary tuberculosis, the application of deep learning to medical topics, and highlights from this issue of Ewha Medical Journal
    Hae-Sun Chung
    Ewha Medical Journal.2025; 48(2): e16.     CrossRef
  • 708 View
  • 31 Download
  • 1 Crossref
Correspondence
[English]
Korea’s 2024 reduction in medical research output amid physician residents’ resignation
Jeong-Ju Yoo, Hyun Bin Choi, Young-Seok Kim, Sang Gyune Kim
Ewha Med J 2025;48(2):e36.   Published online April 17, 2025
DOI: https://doi.org/10.12771/emj.2025.00381
Funded: Soonchunhyang University
  • 454 View
  • 13 Download
TOP