This present study was performed to evaluate the comedogenicity of several cosmetics. The test materials were applied to one ear canal of three rabbits daily for 6 weekdays for 2 weeks.
The results were as follow :
1) Among the 14 cosmetics, extremely weak comedogenicity was shown in one cosmetic, mild comedogenicity in 10 cosmetics and moderate comedogenicity in 3 cosmetics.
2) There were no significant differences of comedogenicity among cosmetic species.
3) The rabbit ear assay was a rapid, effective screening test for evaluation of comedogenicity of cosmetics.
Focal acral hyperkeratosis is clinically identical to acrokeratoelastoidosis but histologically lacks the elastorrhexis which is a feature of acrokeratoelastoidosis. We present a case of focal acral hyperkeratosis in a 50 year old woman. About 20 years ago, a few pinhead sized papules developed on radial side of index fingers. Thereafter size and number of papules have been gradually increased to cover entire hands sparing palms and dorsa of feet. The histopathologic study showed characteristic findings of focal acral hyperkeratosis. After treatment with etretinate, the size and thickness of lesions were reduced.
We present two cases of childhood dermatomyositis. Case 1 was a 4 year old girl who developed erythematous swelling on the face, violaceous papules on the dorsum of the hands, and progressive muscle weakness which led to walking difficulty. Case 2 was a 11 year old girl who had diffuse erythematous confluent patches with fine scales on the face. Poikilodermatous changes on the whole body and progressive muscle weakness in lower extremities developed. These cases were confirmed by clinical appearance, laboratory findings and histopathologic findings.