The change of the skin are acute reaction of erythema or sunburn, and/or prolonged and accumulated exposure commonly associated with degenerative changes, skin, aging, actinic keratosis and carcinoma after exposure to ultraviolet light. Topically applied protective agents are screen or barriers, absorb light of a particular wavelength or reflect it, which protect viable cells and has been used to decrease the risk of development, to prevent exacerbation of photodermatoses, pigmentary disorders, as melasma and freckles. The purpose of the study was to evaluate and comparative the several sunscreen agents available on the human skin of 40 healthy volunteers by indoor method and sunlight. The results were as follows: 1. In the development of minimal erythema doses, the average noted 4.8 minutes in ultraviolet light-B, 12.6 minutes in ultraviolet light-A, and 15.4 minutes in sunlight. 2. The sunprotective factors of 1.7% p-aminobenzoic acid, 0.3% benzophenone in cream were 12.1 in ultraviolet light-B, 8.2 in ultraviolet light-A, 6.3 in sunlight with highest effectiveness, and that of 5% p-amino-benzoic acid in oil were 1.6, 2.4, 1.3 with lowest effectiveness. 3. 1.7% p-aminobenzoic acid, 0.3% benzophenone in cream gave protection similar to that of 5% p-aminobenzoic acid in 70% ethylalcohol. 4. In the vehicle, the effectiveness of alcohol type agent is better than that of oil type of 5% p-aminobenzoic acid.

The clinical studies were made on 500 cases of acne vulgaris who visited to Department of Dermatology, Ewha Womans University Hospital during from January, 1978 to June, 1980. The result were as followings; 1) Among 500 cases, 69(13.8%) were male patients, 431(66.2%) were female patients. 2) In the duration of the skin lesion from onset to be diagnosed, under 1 year was 63.0% (315 cases), and especially under 6 months was 50.4% (252 cases). 3) In the visiting frequency once was 38.4%(192 cases), and in the male was 42.0% (29 cases), and female was 37.8% (163 cases). 4) In the site of the skin lesion, face alone (90.0%), face and neck (3.8), face and chest (3.2%), face and back (2.0%), face and trunk (1.0%), were ordere. 5) In the factors affecting the severity of lesion, fatigue (26.8%), menstrual pentod (23.4%), gastrointestinal trouble (11.8%), cosmetics (9.0%), seasonal changes(5.4%), and unknown (23.6%) were revealed. 6) 309 cases having surgical treatment, 36.8% of once and 11.4% of twice were revealed.

Two cases of subcorneal pustular dermatosis are presented. The clinical and histopathological findings are discussed. In case 1, treatment of combination of dapsone and corticosteroids was relatively ineffective. In case 2, treatment with combination of dapsone, ultraviolet light, and triamcinilone intralesional injection, was satisfactory clinical response transiently, but complete remission could not obtained.