| Kyu-Kwang Whang | 5 Articles |
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[English]
The field of dermatologic surgery has seen trementdous developments in the past few years. Our purpose was to discuss current statistical data on the dermatologic patients treated by surgical methods at our institute. We analyzed 2,334 cases of surgeries performed on 1,075 patients at the Department of Dermatology of Ewha Womans University Tongdaemun Hospital during a period of 5 years (1994. 1 - 1998. 12). The results are summarized as folows: 1) Of the 2,334 cases of surgeries, 846 cases(36.2%) were chemical peelings, 650 cases(27.8%) cryosurgeries, 255 cases(10.9%) CO2, lasers, 209 cases(8.9%) dermabrasions, 113 cases(4.8%) scalpel surgeries, 61 cases(2.6%) Mohs micrographic surgeries, 50 cases(21.1%) sclerotherapy, 48 cases(2.0%) flap repair surgeries, 35 cases(1.5%) punch elevations, 15 cases(0.6%) hair transplantations, 13 cases(0.5%) epidermal grafts, and 2 cases(0.1%) autologous fat/collagen transplantations. 2) The ratio of male to female was 1 : 2.4 and the mean age of patients was 30.3 years. 3) A total of 1,354 cases of diseases were managed surgically : among them, the most frequent disease was scar(39.8%), followed by pigmentary disorders(30.8%), and benign or malignant tumors(21.2%). 4) With respect to the types of scars, acne scar was treated most frequently by chemical peeling (72.7% of 580 cases), atrophic scar by dermabrasion(37.3% of 126 cases), and hypertrophic scar (including burn scars) by cryosurgery(35.3% of 85 cases).
[English]
We report a case of type III hyperlipoproteinemia associated with tuberous xanthoma, which is improved by treatment with lovastatin and bezafibrate. A 34-year-old female patient visited our clinic for evaluation of multiple yellowish-brown papulonodules on the kness, elbows and palms. Serum lipid examination showed an abnormal elevation of serum cholesterol and triglyceride. Lipoprotein electrophoresis showed a single peak at pre-β and β portion without separation. The biopsh specimen from a nodule on the knee and a papule on the palm revealed characteristic findings of xanthoma. We diagnosed the case as type III hyperlipoprotei-nemia. After 3 months of treatment with diet restriction, lovastatin and bezafibrate, the serum levels of cholesterol and triglyceride were reduced to normal level. The skin lesion of the palm showed complete regression and ones on both knees and elbows were moderate improvement.
[English]
This study attempts to evaluate the clinical manifestations and causative drugs of drug eruptions at Ewha Womans University Tongdaemun Hospital by retrospective study of outpatients, inpatients and consulted patients(number : 121, duration : 1994. 1 - 1999. 5). 1) Most drug eruptions occurred in patients at the age of 20 - 39 years old. 2) The cutaneous manifestations of drug eruptions in the order of frequency were as follows : exanthematous eruption, fixed drug eruption, acneiform eruption, purpura, urticaria, bullous eruption, lichenoid eruption, Stevens-Johnson syndrome, and acute generalized exanthemic pustulosis. 3) Drug eruption developed most frequently from 24 hours to 3 days of drug intake. 4) Most common causative drugs were antibiotics, followed by antipyretics and analgesics. 5) Laboratory abnormalities were leukocytosis(22.5%), eosinophilia(14.5%), abnormal AST/ALT(11.4%), abnormal IgE titer(8.3%), and leukopenia(5.6%). The most frequent clinical feature of the drug eruption were exanthematous in nature and the most common causative drugs were antibiotics, as suspected. Since too many patients take various unidentified drugs at drug stores in Korea, physicians need to exercise special care in prescribing drugs and evaluating patients with drug eruption.
[English]
The purpose of this study is to evaluate the therapeutic effect and clinical applicability of 5% sodium morrhuate sclerotherapy as primary surgical approach in cases of mucous systs. 15 cases of mucous cysts who were treated with 5% sodium morrhuate sclerotherapy were evaluated and 11 cases were followed up during 1994's. First, mucous cyst was incised, and washed out several times. 5% sodium morrhuate was infused slowly(More than 5 minutes) and throughly for maximal contact. Pressure dressing was done with elastic bandage for 2-3 days. Age of patients were distributed form 12 year-old to 44 year-old. Involved sites were wrist97), thumb(2), ear(1), and hand(1). 5 cases among 11 cases(45%) were cured completely, but 6 cases(55%) were reoccurred, Timing of recurrences were distributed from 2-3 days till 4 months, and mean was 40 days. Patients assessed the satisfactions of therapy as excellent 2, good 1, fair 1, poor 7. complications were mild pain, hardening, and pigmentary change. 5% sodium morrhuate sclerotherapy might be useful as a primary surgical approach in cases of mucous systs because of simplicity. It is expected that therapeutic effects of sclerotherapy would be improved by repeated applications, changing to more potent sclerosants and meticulous pressure method.
[English]
Sclerotherapy has become a popular method for obliterating both varicose veins and telangiectases. Through the animal model of sclerotherapy, we would understand its mechanism as a basis of clinical application. Clinical and histologic changes were observed periodically after injecting the hypertonic saline into the dorsal marginal rabbit ear vein, and the results were as follows. There was no color and diameter changes in the vein after the normal saline injection as a control. Clinical changes after injection of sclerosant were that the color of vein changed to blue or dark blue at the early period, and it eas faded out one month later. Histologic examination after injection of sclerocant showed the intravascular thrombosis, cutaneous necrosis, vascular proliferations, and fibrosis at the early period, and large vein was disappeared and replaced by several telangiectasis and matured fibrosis one month later. We could predict the outcome clinically and histologically, and the complication like cutanceous necrosis should be warned during the clinical application.
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, Min-Jung Kang
