We presented here a patient of autoimmune hemolytic anemia associated with systemic lupus erythematosus. This 38 year old female was admitted because of dizziness and dyspnea. In peripheral blood and bone marrow study, characteristics of autoimmune hemolytic anemia were seen. And she was well treated with prednisolone only. The general concept of autoimmune hemolytic anemia with the brief review of literature is discussed.

Gilbert's Syndrome is the name most frequently used to describe a condition which has been called constitutional heptic dysfunction, familial nonhemolytic jaundice of icterus intermittens juvenilis. It is characterized by a benign, persistent, but variable elevation of the plasma unconjugated bilirubin. A 27-year-old man was admitted because of general malaise, anorexia, sore throat and slight icteric sclera. On physical examination, there were mild icteric sclera and slightly injected pharynx. The liver was palpable 1 finger breath BRCM and the spleen was also palpable I finger breadth BLCM. Hematologic studies revealed slight anemia with slightly elevated corrected reticulocyte count. Liver function tests were normal except for slightly elevated serum total bilirbin. Histolog-ic findings of the liver showed nonspecific findings of mild cholestasis. Reduction in caloric intake to 300 calrory a day for 72 hours resulted in a significant increase in the plasma bilirubin concentration(especially unconjugated form) in this patient. Now he has no subjective symptoms and leads a normal activity without specific treatment.

Citations

Citations to this article as recorded by  

• A Case of Congenital Hemolytic Anemia of Unknown Cause Combined with Gilbert's Syndrome
  Ji Whan Lim, Joon Hyouk Choi, Yang Hoon Nam, In Seok Seo, Seong Min Yoon, Myoung Sook Koo
  The Korean Journal of Hematology.2008; 43(1): 58.     CrossRef

The infiltrative carcinoma of stomach is reported to difficult to diagnosis by gastroscopic examination only, because of a few change of mucosa. So the tumor is diagnosed with the aid of gastroscopic multiple biopsy findings. We experienced a case of infiltrative carcinoma of stomach, which was similar to hypertrophic gastritis. The tumor was confirmed by the biopsy and operation finding. The general concept of infiltrative carcinoma of stomach with the brief review of literature is discussed here.