Facial melanosis may be distinguished on the basis of etiology, associated morphologic changes, and distribution. Factors contributing to the development of such pigmentation are contact dermatitis, sun exposure, systemic hormonal alterations, and toxic substances. Among these facial disorders may be listed; melasma, postinflammatory hyperpigmentation, Riehl's melanosis, and mercurial pigmentation. In order to compare facial melanosis, Ewha Womans University Hospital studied 1977 patients from July 1,1980 to June 30, 1981. The results were as follows: 1. The favorite site of melasma was cheek, malar prominences, and forehead in that order. Postinflammatiry hyperpigmentation occurred on the forehead, malar prominences, and the cheek in that order. Riehl's melano-sis developed on the face and mercurial pigmentation was on the cheek, malar prominences, and forehead. 2. The color of melasma was mostly brown, dark brown and subsequently light brown in that order. Postinflammatory hyperpigmentation was mostly dark brown, brown and subsequently light brown in that order. The color of Riehl's melanosis and mercurial pigmentation was dark brown. 3. In spring and summer seasons, melasma, postinflammatory hyperpigmentation and Riehl's melanosis were exacerbated by sunlight, but mercurial pigmentation was not affected by sunlight. 4. In all 19 cases (melasma 12 cases, postinflammatory hyperpigmentation 4 cases, Riehl's melanosis 2 cases, mercurial pigmentation 1 case) the C.B.C., urinalysis and liver function tests, were within normal limits. 5. In 19 cases biopsy specimens revealed an increase of melanin pigment and chronic inflammatory cell infiltration. In one case, the findings were similar to those of a tattoo biopsy and 2 cases showed free zone beneath the papillary body. Patients with facial melanosis, characteristically have a similar history, clinical and laboratory findings, and disease course.

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The clinical studies were made on 500 cases of acne vulgaris who visited to Department of Dermatology, Ewha Womans University Hospital during from January, 1978 to June, 1980. The result were as followings; 1) Among 500 cases, 69(13.8%) were male patients, 431(66.2%) were female patients. 2) In the duration of the skin lesion from onset to be diagnosed, under 1 year was 63.0% (315 cases), and especially under 6 months was 50.4% (252 cases). 3) In the visiting frequency once was 38.4%(192 cases), and in the male was 42.0% (29 cases), and female was 37.8% (163 cases). 4) In the site of the skin lesion, face alone (90.0%), face and neck (3.8), face and chest (3.2%), face and back (2.0%), face and trunk (1.0%), were ordere. 5) In the factors affecting the severity of lesion, fatigue (26.8%), menstrual pentod (23.4%), gastrointestinal trouble (11.8%), cosmetics (9.0%), seasonal changes(5.4%), and unknown (23.6%) were revealed. 6) 309 cases having surgical treatment, 36.8% of once and 11.4% of twice were revealed.