Angiolymphoid hyperplasia with eosinophilia(ALHE) is a benign, uncommon disorder of unknown etiology and usually appears as intradermal or subcutaneous, red to brown papules and/or nodules, usually located on the head and neck region, and occurring in young adults.

Histopathologically ALHE is an angiolymphoproliferative lesion which shows characteristically plump epitheloid or histioid endothelial cells, accompanied by an inflammatory infiltrate that mainly consists of lymphocytes and eosinophils.

We reported a case of angiolymphoid hypreplasia with eosinophilia occurring on the scalp in a 52-year-old female and review the literature.

Prurigo pigmentosa is an inflammatory dermatosis characterized by severe pruritic red papules and coarse reticulated hyperpigmentation. More than 300 cases have been reported in Japan and several cases have also been described in Caucasians. It is more common in young adult females, particularly in adolescence, but may sometimes occur in males and older persons. The lesions occur mainly on the trunk and neck with severe itching. The histopathologic findings are not specific but occasionally show lichenoid tissue reaction. The etiology of this disease still remains unknown.

We reported a case of prurigo pigmentosa in a 26-year-old-male, which clinically and histopathologically fulfilled the characteristics of prurigo pigmentosa and was treated with dapsone resulting in significant clinical improvement.

Merkel cell carcinoma is a rare aggressive tumor of uncertain origin. The tumor occurres most commonly in the head and neck region of the eldery.

The patient was a 62-year-old female with a reddish nonulcerative movable hard nodule on her left temple area for 2 months. Histopathologically, the tumor cells with large vesicular nuclei and scanty cytoplasm were arranged in trabecular and cord-like pattern in the dermis. The majority of the tumor cells were positive for neuron specific enolase, chromogranin and neurofilament.