More than 30 years have passed since Dr. Whipple discribed a 2 stage resection for cancer of pancreas in 1935. Through these years, there has been varying enthusiasm for pancreaticoduodenal resection in the management of pancreatic cancer, but high incidence of post-operative complication and mortality were still remained. This 61 years old male patient was admitted to our hospital on 10th December. Physical examination revealed marked yellowish discoloration on entire body, systemic edema, and non-tender palpeble right upper quadrant mass. Liver function tests revealed remarkablly increase level of glucose, total bilirubin, S.G.O.T. and S.G.P.T. E.R.C.P. was suggest pancreatic pseudocyst. Pancreatic biospy from shows infiltration by atypical gland with filbrosis with final diagnosis of pancreatic adenocarcinoma. This paper is concerned with our experience of drainage procedure of the extensively involved pancreatic cancer and reviewed with current oncepts in the manageme nt in literature.
A case of leiomyosarcoma in stomach is reported with is rare disease and good prognosis rather than other adenocarcinoma of stomach. The tumor occurs in approximately equal frequency in both sex. It is seen at a somewhat young age than carcinoma of the stomach. This 26 year old female patient was admitted to our hospital on 14th Oct. 1930, with melena, dizziness and epigatstric mass. Physical examination revealed pale conjunctiva and questionable ill-defineed mass was palpated in the epigastric region. The C.B.C was obtained R.B.C.I. 8 million/mm3, HB. 5.0gm%, Hct. 15%, and W.B.C. 5,500/mm3 (Neutrophil seg. 70% and Lymphocyte 30%.) The upper G-I series showed multilobulated mass in lesser curvature of stomach. The massed have smooth and sharp bordered and overlying mucosa shows marked effacement. Superficial ulceration is also noted in the lesion. There is no evidence of rigidity or passage disturbance. Remain stomach and duodenum are within normal limit. Pathological examination was noted; multile, large, bulky intra-luminal massed are seen in the lesser curvature, with fungate into the gastric lumen and project subserosally. However, sections from tumor show non encapsulated multinodular tumor consisting of spindle and polygonal, moderately pleomorphic tumor cell by microscopy. There are some tumor cells arranged in whirl pattern with edematous highly vascularized stroma. Occasionally mitosis was vasible. This paper is concerned with our experience of a rare case of leiomyosarcoma of the stomach and reviewed with current concepts in the management in the literature.