We report two cases of dengue fever due to DENV-1 in the family members who returned from Manila, Philippines. Case 1: A 41-year-old female visited the clinic with a general weakness. She had a fever for 5 days. When she came back to Korea, her fever had subsided. The immunoglobulin M (IgM)-capture enzyme-linked immunosorbent assay for dengue virus was positive. Case 2: A 11-year-old female was admitted to the pediatric department after reporting symptoms of fever and abdominal pain upon returning from the Philippines. The RT-PCR result for DENV-1 was positive in blood, but IgM came out negative. Dengue fever should be suspected for those who have returned from an endemic area with reports of febrile illness and rash, particularly if thrombocytopenia, leukopenia, elevated serum aminotransferase are present. Using RT-PCR and serological test, the precise diagnosis should be made and proper management should be given to prevent secondary complications.

Citations

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• A Pediatric Case of Dengue Fever with Extreme Hyperglycemia Developed in a Family Who Returned from India
  Joon Young Kim, Han Wool Kim
  Pediatric Infection & Vaccine.2020; 27(2): 140.     CrossRef
• Eight Cases of Dengue Fever in a Volunteer Group from Sri Lanka and Its Ocular Involvement
  Ji Yeon Lee, Hyun Ah Kim, Yu Cheol Kim, Seong Yeol Ryu
  The Korean Journal of Medicine.2017; 92(5): 484.     CrossRef