Young Sik Lee | 2 Articles |
[English]
We retrospectively reviewed chest radiographs of 101 patients with primary pneumonia treatedat department of pediatrics between January 1990 and June 1992 to understand pnelimoniaradiologic patterns in ages of children and to attain helpful information in diagnosing pediaoicpneumonia hereafter. Results were as follows : 1) The cases of infantile pneumonia (under 1 year of age) were 42. The most frequent Hadingwas peribronchial infiltration with overaeration(24 cases, 57.1% ), followed by multiple patchyatelectasis associated with peribronchial infiltration and overaeration(8 cases, 19.0%). parahilarperibronchial infiltration (5 cases. 11.9%), peribronchial infiltration and air space consolidation(2 cases,4.8%), air space consolidation(2 cases,4.8%) and bronchopneumonia pattern(1 case,2.4%). 2) The cases of 1~6 years of age were 52. The most common finding was parahilar peribron-chial infiltration(29 cases, 55.8%), followed by air space consolidation(13 cases. 25.0%), andbronchopneumonia pattern(10 cases, 19,2%). 3) The rases of 7~13 years of age were 7. All cases showed air space consolidation.Under 6 years of age, the radiographic findings of pneumonia differed from that of adult. Over 7 years of age, the pattern of pneumonia was similar to that of adult.
[English]
Radiobiological and clinical evidences indicate that irradiation combined with hyperthermia produce a significant improvement in therapeutic effect of cancer. Hyperthermia can enhance the radiation effect as a synergistic reaction in irradiation combined with hyperthermia. Hyperthermia sensitize radioresistant S-phase and inhibit cellular recovery from the sublethal damage. Ninety guinea pigs were divided into 4 groups for the experiment of application of irradiation combined with hyperthermia on their heart; (1) normal control group. (2) group receiving only hperthermia. (3) group receiving a single dose of irradiation of 10, 20 and 30 Gy resepectively. (4) group receiving varying single dose of irradiation like group (3) irradiation combined hyperthermia. Heating by 100 watt. 2450 MHz microwave hyperthermia on the heart was applied for 30 minutes maintaining 42~45℃ immediately following irradiation. Microscopic examination and calculation of thermal enhancement ratio were carried out and results were as follows: 1) Hyperthermia alone did not evoke much changes. compared to normal control group. 2) In the group of irradiation alone. myocrdial muscle degeneration was noted in l0Gy irradiation and its severity was increased along with radiation dose. 3) In the group of irradiation alone. myocardial muscle necrosis was noted at 15 days after 20Gy irradiation. In the group of irradiation cmbined with hyperthermia. myocardial muscle necrosis was noted in l0Gy irradiation. 4) In the group of irradiation alone, interstitial fibrosis was noted at 15 days after 30Gy irradiation. In the group of irradiation combined with hyperthermia. interstitial fibrosis was noted at 15 days after 20Gy irradiation and its severity was increased along with radiation dose. 5) The thermal enhancement ratio(TER) was 1.5 on the end point of interstitial fibrosis of the guinea pig heart.
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