Recently, antibiotic resistant organisms have increasing tendency. So, we studied causative organisms in urinary tract infection and investigated the resistance to each antibiotics.

From January 2004 to March 2004, uropathogens and antibiotic sensitivity tests in urine culture of patients with urinary tract infection were analyzed retrospectively. One hundredeleven women and 51 men in 168 adults were included.

Incidence of positive urine culture was 66.1% in women, and 33.9% in men. Mean age was 62.6 years old in men, and 61.7 years old in women. The most common uropathogen was E. coli(50.4%), followed by K. pneumoniae or(21.3%), P. aeruginosa(9.2%). In adult men, the most common uropathogen was S. marceacencs(46.5%). E. coli has the resistance to almost all antibiotics. In E. coli, the resistant rates on each antibiotic were ampicillin(73.8%), piperacillin(66.7%), levofloxacin(37.2%), gentamicin(35.8%), TMP/SMX(31.7%). ciprofloxacin(30.3%) inodor. Extended Spectrum β-lactamase(ESBL) producing organisms were found in E. coli(20 patients) and K. pneumoniae(3 patients).

E. coli was the most common uropathogen. Especially, ESBL producing organisms were Increasing.