Chronic kidney disease(CKD) and Sexual dysfunction are important public health problems in older man as a part of life. We investigated the relationship between two groups.
We examined sixty-five CKD patients on glomerular filtration rate (GFR), serum creatinine (sCr), Prevalence period and causative disease. Sexual function was evaluated by International Index of Erectile Function(IIEF-5), libido(2 items), ejaculation(4 items), frequency of sex in a month and serum testosterone. A control group composed of eighteen male adults who had visited to the general medical testing center in the hospital. They didn't have any combined disease and they were similar age range to the group of the CKD. We analyzed correlations between components of the CKD and sexual function.
The study revealed that all sexual components of the CKD group(mean age 51.8±2.6) were significantly worse than the control group; 12.3±3.9 of IIEF-5, 5.4±1.8 of libido and 10.1±2.2 of ejaculation, 1.4±0.7times of sex in a month in the CKD group and 18.3±3.5 of IIEF-5, 7.2±2.1 of libido and 15.3±2.9 of ejaculation, 2.9±1.1 times of sex in a month in the control group. The patients whose prevalence period of CKD was over than 3 years or whose sCr was over than 2.0ng/ml, had all sexual components worse significantly. Comparing by the causative disease of the CKD, there was no any significant difference. Analyzing by correlation, erectile function is related with serum glucose, sCr, Prevalence periods and libido is related with prevalence periods, and ejaculation is related with diabetes.
The patients with CKD may have a sexual dysfunction that make erection, libido and ejaculation and the number of their sex seemed to decrease. Therefore we need to have more attention to their sexual function as an important part of life.
Citations
The aim of this study was to analyze the diskibution pattern of the 38 mineral elements in the patients with chronic urogenital diseases such as benign prostatic hyperplasia(BPH), andropause, erectile dysfunction, menopause, overactive bladder and stress urinary incontinence, which were appeared as the result of various life factors including the ageing.
Hairs were collected in the occipital scalp area and analyzed mineral status in theme thod of inductive coupled plasma mass spectroscopy (Trace Element, INC. ; TEI, USA). 15mandatory nourishment minerals, 15 additional minerals,8 heavy metals and the ratio of Ca/P Na/K, Ca/K, Zn/cu, Na/Mg, Ca/Mg, Fe/Cu were measured. The results were classified as each disease and compared.
The disease which showed high rate of patient with increased calcium was menopause(85.7%) and overactive bladder (OAB) (61.9%). The disease which showed high rate of patient with increased magnesium was menopause (57.1%). The disease which showed high rate of patient with increased sodium was stress urinary incontinence (SH) (42.9%). Other minerals didn't show particular distribution by the disease. The average ratio of Caf was increased in all diseases and the degree of the increase was high in menopause, OAB and SUI. The average ratio of Zn/Cu was increased only in menopause. The average ratio of Ca/K was increased in all diseases and the degree of the increase was high in menopause, OAB and SH. The average ratio of Zn/Cu was within normal range in all diseases. The average ratio of Na/Mg was increased only in BPH and was decreased in menopause, andropause and OAB. The average ratio of Ca/Mg was increased in all diseases and the degree of the increase was the highest in OAB.
The distribution pattern of mineral elements according to chronic urogenital diseases was distinctive. Thus we consider that mineral supplement remedies suitable to the eachdisease can be recommended.