, Sun Young Yi, Hye-Kyung Jung, Seong-Eun Kim The purpose of this study was to compare the safety and efficacy of midazolam sedated Endoscopic retrograde cholangiopancreatography (ERCP) with unsedated ERCP in patients 70 years of ages and older.
Seventy elderly patients 70 years of age or older who underwent ERCP were divided into two groups: midazolam sedated group (n=43) and unsedated group (n=27). Procedure time, success rate, complications related with ERCP procedure, satisfaction score were analyzed between two groups.
Mean procedure time was 20.6 minutes for sedated group and 21.0 minutes for unsedated group (P=0.88). Success rate was 87.5% for sedated group and 100% for unsedated group (P=0.07). Incidence of complications from ERCP procedure showed no significant differences between the sedated and unsedated groups (P=0.10). There was no mortality in both groups related to the sedation or post-ERCP complication. Compared to the unsedated procedure, the sedated ERCP procedure was associated with higher patient satisfaction (P<0.001) and better repeat compliance (P=0.004).
There was no significant difference in success rate and complications at sedated and unsedated ERCP in patients 70 years of age and older. Unsedated ERCP showed 66.6% satisfaction score compared to sedated ERCP.
As the general population ages increase leading to an increase in the demand for therapeutic ERCP interventions. The aims of this study are to assess the outcomes, safety and complications associated with ERCP performed in elderly patients.
ERCP was performed in 287 patients aged 70years or over from Jan. 2000 to Dec. 2005. All the patients were evaluated and retrospectively reviewed. The main indications, complications, success rate, mortality and risk factors of procedure were analysed.
287 patients(162 females and 122 males, mean age 78 years, range 70-94years) underwent diagnostic and therapeutic ERCP. Mortality rate was 0.03% and success rate was 91.7%. Minor complications including procedure-related complications such as pancreatitis(2.8%), minor bleeding(1.4%), and aggravated cholangitis(2.1%), mild hypoxia(SaO2 < 90%, 15.1%), premature ventral contraction(1.0%), and tachycardia(50.7%) were transient. Major events were presented as severe hypoxia(SaO2 < 85%) in three pts(1.0%), and atrial fibrillation in one patients (0.03%).
This study showed that diagnostic and therapeutic ERCP is safe in elderly patients. Minor complications are usually transient and mortality is similar to previous reported rate.
First
Prev
