, Mi Ae Lee, Ho Jung Kang, Jeong Hee Hahm Contact dermatitis is a common clinical problem and frequently caused by cosmetics. Detection of causative allergen is important in prevention and treatment of this disease. Patch rest has been accepted as the only reliable diagnostic method to detect allergens. We analyzed patch test results of dermatologic outpatients and evaluated common new antigens producing cosmetic and noncosmetic contact dermatitis.
We reviewed patch test results of the 324 patients with suggestion contact dermatitis who had visited our department from May 1985 to February 1996. We divided the patients in two groups(cosmetic contact dermatitis group and non-cosmetic contact dermatitis group)and compared the results.
1) High positive reaction rate to nickel sulfate(14.7%), fragrance mix(11.0%), and mercury ammonium chloride(9.6%) was seen in cosmetic contact dermatitis group. Lip cosmetics and make-up preparation were the products to which patients reacted the most. Among the cosmetic products, skin care products ranked the first in positive reaction rate.
2) Nickel sulfate(21.7%) was the most common allergen, followed by cobalt chloride(13.3%), mercury ammonium chloride(10.0%), and fragrance mix(8.3%) in noncosmetic contact dermatitis.
Consmetic contact dermatitis was more common than noncosmetic contact dermatits. Nickel sulfate, mercury ammonium chloride, cobalt chloride and fragrance mix were found to be the most common allergens of cosmetic and noncosmetic contact dermatitis.
, Ho Jung Kang, Jeong Hee Hahm The use of rubber gloves has increased in recent years. At the same time, there has been a progressive increase of incidence of occupational and nonoccupational sensitization to rubber components. Chromate sensitivity has been reported as a very common combination in the rubber allergic building workers.
We report a case of contact dermatitis to rubber glove and cement in a 69-year-old man who presented erythematous patches with severe itching on both hands, especially on the lateral sides of fingers. On patch tst, he showed positive reactions to thiuram mix, mercaptobenzothazole, potassium dichromate and rubber glove as is.
The patient was treated with topical and sysmetic corticosteroid and antihistamine with a good clinical responses.
, Hyun Joo Kim, Seung Lee Seo, Young Sook Kim, Mi Ae Lee, Jeong Hee Hahm Levofloxacin, an oral fluroquinolone antibacterial agent, is the optical S-(-) isomer of ofloxacin. In vitro it is generally twice as potent as ofloxacin and active against most aerobic gram positive and gram negative organisms, but only moderate activities against anaerobics.
Our purpose was to investigate the therapeutic efficacy and tolerability of levofloxacin in patients with several kinds of cutaneous infections.
Levofloxacin(CRAVIT®; Korea Daiich Parm. Co.) 300-600mg/day for 5-14days was administrated to eighteen patients with cutaneous and subcutaneous infections. The Bacterial culture and laboratory tests were performed prior to and after treatments. Clinical effects and adverse events were evaluated on laboratory indics.
1) Nine of thrteen cases(70%) were useful, four cases(30%) were slightly useful.
2) Clinically twelve of eighteen cases were cured and eight cases were partial response to the drug.
3) There were no laboratory abnormalities after levofloxacin treatment
4) Side effects were not significant except dizziness and sleep disturbance.
Levofloxacin was evaluated as a highly effective antibacterial agent against dermatologic infections.
Citations
First
Prev
