The pacemaker syndrome is a complex of clinical signs and symptoms related to the adverse hemodynamic and electrophysiologic consequence of ventricular pacing in the absence of other cause.

The following illustrates a case of pacemaker syndrome proven by cardiac catheterization. A 64-year-old female patient who had been previously managed with single chamber pacemaker(VVI mode) due to sick sinus syndrome, suffered from chest discomfort, headache, dizziness, lightheadedness.

We thought that she suffered from pacemaker syndrome and changed single chamber pacing to dual chamber pacing. At that time we performed cardiac catheterization perioperatively.

Pulmonary capillary wedge pressure, amin pulmonary arterial pressure, right atrial pressure and right ventricular pressure were normalized after the change and she didn't feel any symptoms.

Heat stoke is a life-threatening syndrome of multi-organ dysfunction caused by elevated body temperature. Reported mortality rate range from 17-70 percent. The heat stoke victim's circulatory pattern id defined low peripheral vascular resistance and high circulatory demand of other conditions involving tissue injury such as trauma or sepsis. Owing to either to direct thermal injury of the myocardium or to increased pulmonary vascular resistance, the heart may not meet the elevated circulatory demand. Heat stoke induced cardiomyopathy is diagnosed by pathlogy, EKG abnormality, LDH isoenzyme, echocardiography. Therapy was two purpose : rapid reduction of body temporature and support of the cardiovascular system. We experienced a case of heat stoke induced cardiomyopathy in a 21 year-old male who had been observed for 1 years. The Left Ventricular End-Diastolic Diameter(LVEDD) was 65mm, Ejection fraction(EF) was 35% initially and LVEDD was decreased 58mm, EF was 60% after 9 months. We report a case of heat stoke induced cardiomyopathy with brief review of literature.