Dentigerous cyst represents cystic enlargement of the follicle of an impacted tooth. It is the sites of predilection mirror the favored sites if impacted teeth : mandibular third molars, maxillary third molars, and maxillary canines. These cysts are most prevalent in the second to fourth decades. Most cysts are asymmetric and are discovered on routine dental radiographs, but large examples can cause displacement or resorption of adjacent teeth and infection. Microscopical examination discloses a stratified squamous epithelium covering a fibrocollagenous cyst wall.

In this case, authors present a case of huge dentigerous cyst on right piriform fossa across the midline that enucleated successfully through the right gingivobuccal approach.