The diffuse interstitial lung diseases are a heterogeneous group of diffuse inflammatory disorders of the lower respiratory tract characterized by derangements of the alveolar walls and loss of functional alveolar capillary units. The most common causes of diffuse interstitial lung diseases are idiopathic pulmonary fibrosis, sarcoidosis, collagen vascular disorders, hypersensitivity pneumonitis and pneumoconiosis. Especially, the miliary tuberculosis is also leading cause in Korea, but pulmonary tuberculosis presenting as diffuse interstitial lung disease except miliary tubercuaosis is rare. We report a case of pulmonary tuberculosis presenting as diffuse interstitial lung disease associated with the tyrnphadenopathy of mediastinum and abdomen.
Acute eosinophilic pneumonia is characterized by acute febrile disease with diffuse interstitial infiltration on chest radiography, eosinophilic infiltration of lung parenchyma on lung biopsy and good response at corticosteroid therapy. There has been several reports that support cigarette smoking recently, even though the pathogenesis is not clear. We encountered a case of acute eosinophilic pneumonia induced by cigarette smoking, who, being a 20-year-old man, presented with acute onset of fever after his first cigarette smoking. His clinical symptoms and the infiltrations on onset x-ray improved after a treatment with corticosteroid.