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"Moo-Nyun Jin"

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"Moo-Nyun Jin"

Case Reports
[English]
Cytomegalovirus Colitis with Colon Perforation and Lower Gastrointestinal Bleeding in a Immunocompetent Patient
Sun Wook Kim, Yoon Jin Cha, Min Hwan Kim, Moo-Nyun Jin, Jung-Hee Lee, Hye Jung Park, Sooyun Chang, Hyuk Lee
Ewha Med J 2014;37(2):105-108.   Published online September 30, 2014
DOI: https://doi.org/10.12771/emj.2014.37.2.105

Cytomegalovirus (CMV) infection in immunocompromised patients is associated with significant morbidity, mortality, and adverse clinical outcome. However, CMV infection in immunocompetent patients has been considered to have subclinical and self-limited course, and does not require treatment. We reports a case of CMV colitis, presented with colon perforation and lower gastrointestinal bleeding in a immunocompetent 31-year-old young male. After conservative treatment, colonoscopy revealed multiple ulcers in transverse colon. CMV colitis was confirmed by microscopic findings and immunohistochemistry. After successful treatment with ganciclovir, the patient improved without invasive procedure.

Citations

Citations to this article as recorded by  
  • Gastric Ulcers with Cytomegalovirus Infection in an Immunocompetent Patient
    Tae Oh Kim, Ki-Nam Shim, Sang Yoon Kim, Ji Young Lim, A Reum Choe, Chung Hyun Tae, Chang Mo Moon, Seong-Eun Kim, Hye-Kyung Jung, Sung-Ae Jung
    The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2019; 19(4): 277.     CrossRef
  • Conservative treatment of cytomegalovirus colitis with bowel perforation in an immunocompetent patient: case report and review of literature
    Kyoung Sik Nam, Hee Ug Park, Min Gi Park, Su Ho Park, Ji Yeon Hwang, Dong Kyu Kim, Sung Jun Kim
    Yeungnam University Journal of Medicine.2017; 34(1): 75.     CrossRef
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[English]
Aortic Valve Replacement after Previous Coronary Artery Bypass Grafting with Patent Internal Mammary Artery
Moo-Nyun Jin, Sun Wook Kim, Young Ju Kim, Hyun Ju Kim, Jung-Hee Lee, Myeong-Ki Hong, Byung-Chul Chang
Ewha Med J 2014;37(1):64-67.   Published online March 25, 2014
DOI: https://doi.org/10.12771/emj.2014.37.1.64

With the aging population, more patients who have undergone previous coronary artery bypass grafting (CABG) are surviving long enough to require subsequent aortic valve replacement (AVR). Conventional redo AVR after prior CABG involves resternotomy, dissection and clamping of the patent bypass graft vessel. Favorable results have been reported for AVR following previous CABG; however, the problems of this procedure includes that injury to the patent bypass grafts can result in catastrophic complications. Increasing patient age and comorbidities may increase operative mortality, less invasive percutaneous aortic valve intervention has advanced. However, because there are no sufficient data comparing transcatheter aortic valve intervention with surgical AVR, currently, the surgical approach should still be consider as the standard of treatment for AVR following previous CABG. We report a patient in whom successful conventional AVR was underwent after previous CABG with patent left internal mammary artery.

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[English]
A Favorable Treatment Response of Erlotinib in Lung Adenocarcinoma with Concomitant Activating EGFR Mutation and ROS1 Rearrangement
Min Hwan Kim, Yehyun Park, Hye Jung Park, Ah-young Ji, Changho Song, Moo-Nyun Jin, Young Ju Kim, Sun Wook Kim, Jung-Hee Lee, In-Soo Kim, Hye Ryun Kim, Joohang Kim, Byoung Chul Cho
Ewha Med J 2014;37(1):46-51.   Published online March 25, 2014
DOI: https://doi.org/10.12771/emj.2014.37.1.46

The rearrangement of c-ros oncogene 1 (ROS1) has been recently identified as an important molecular target in non small cell lung cancer (NSCLC). ROS1 rearrangement and epidermal growth factor receptor (EGFR) mutation were mutually exclusive each other in previous studies, and the clinical implication of co-existence of the two genetic alterations has not been determined. We report a case of 46-year-old female never-smoker NSCLC patient whose tumor harbored ROS1 rearrangement and EGFR mutation concomitantly. She had undergone curative surgery for stage IIIA NSCLC, and the recurrence in left pleura and brain occurred at 2 years after the surgery. She received several lines of chemotherapy including docetaxel plus carboplatin, erlotinib, pemetrexed, and gemcitabine. Erlotinib therapy showed a favorable treatment response with progression-free survival of 9.5 months and partial response of tumor on radiologic evaluations. This case represents a successful erlotinib treatment in a NSCLC patient with concurrent ROS1 rearrangement and EGFR mutation.

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