Rhodotorula species are emergent opportunistic pathogens, Particularly m mmunocompromised patients. Rhodotorula mucilaginosa was the species most frequently recovered, followed by Rhodotorula glutinis. They have been associated with endocarditis, peritonitis, meningitis and catheter-associated fungemia. We experienced a case of catheter-related blood stream infection by rhodotorula glutinis. He was 46-year old man with decompensated liver cirrhosis. He was admitted for esophageal variceal bleeding. Rhodotorula glutinis was identified on blood culture, and amphotericin B was administered for fungemia treatment.