We report a case of mixed connective tissue disease in a 35-year-old woman showing typicallaboratory and clinical features. Clinically she suffered from hand edema, arthritis, proximalmuscle weakness, loss of hair and Raynaud's phenomenon. FANA revealed a speckled epidermal nuclear staining pattern. Analysis of serum showed anti RNP antibody positive and antiSm antibody negative. Anti DHA antibody occurred in low titer. The patient showed a promptreponse to prednisone 0.5mg per body weight without any recurrence.
Cutaneous periarteritis nodosa is a chronic and benign vascular disease in which cutaneous lesions are perdominent without visceral involvement.
We report a case of cutaneous periarteritis nodoas in a 8-year-old boy who presinted tender plaque with hemorrhagic ulceration and telangiectatic patches on the inner side of the right thigh with no visceral involvement. Histologic examination showed panarteritis of small and medium-sized arteries at the dermal-subcutaneous junction.
The patient was treated with prednisolone and dapsone with a good clinical response.