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Case Report

A Case of Hepatoid Adenocarcinoma without Involving Liver Parenchyme

The Ewha Medical Journal 2007;30(1):61-66. Published online: March 30, 2007

*Department of Internal Medicine, Ewha Womans University College of Medicine, Korea.

**Department of General Surgery, Ewha Womans University College of Medicine, Korea.

***Department of Pathology, Ewha Womans University College of Medicine, Korea.

Copyright © 2007. Ewha Womans University School of Medicine

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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  • Hepatoid adenocarcinoma was described by Ishikura in 1985 for the first time. It is a very rare variant of adenocarcinoma characterized by morphological and functional features of hepatocyte differentiation. It is most commonly presented as gastric adenocarcinoma with otherwise unexplained elevation of serum alpha-fetoprotein level. Most of the patients with gastric hepatoid adenocarcinoma were diagnosed in advanced stages having vascular invasion and/or extensive metastasis in liver or lymph nodes. Accordingly, the prognosis of hepatoid adenocarcinoma is dismal. We experienced a typical case of gastric hepatoid adenocarcinoma and described the clinical features.

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      Ihwa Ŭidae chi. 2007;30(1):61-66.   Published online March 30, 2007
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