• Contact us
  • E-Submission

Ewha Med J : The Ewha Medical Journal

OPEN ACCESS
mobile search button mobile menu button
Search
Advanced Search
ABOUT
BROWSE ARTICLES
JOURNAL POLICIES
FOR CONTRIBUTORS

Articles

Page Path

Case Report

Acute Pancreatitis Caused by Dyslipidemia

Sung Bae An, Suk Joon Park, Sang Su Im, Mi Kyung Sung, Byeong Ho Lee, Jang Wook Lee, Jin Hee Park1
The Ewha Medical Journal 2011;34(2):55-59. Published online: September 30, 2011

Department of Internal Medicine, Daerim Saint Mary's Hospital, Seoul, Korea.

1Department of Laboratory Medicine, Daerim Saint Mary's Hospital, Seoul, Korea.

Corresponding author (mybestdoctor@paran.com)

Copyright © 2011. Ewha Womans University School of Medicine

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

  • 45 Views
  • 0 Download
prev next

Full Article

Download PDF Download PDF
  • Hyperlipidemia can be a cause of acute pancreatitis. For example, dyslipidemia classified Fredrickson/WHO classification type I, V can induce acute pancreatitis spontaneously. Secondary hyperlipidemia (DM, alcohol, estrogen, etc.) also can induce acute pancreatitis. High serum amylase level and triglyceride level are hall markers of diagnosis. But lactescent serum interferes with accurate laboratory analysis of amylase. Serum amylase was normal or low in 50% of cases. Clinical course and treatment are similar with other causes of acute pancreatitis. Lipoprotein electrophoresis helps classify dyslipidemia by Fredrickson/WHO classification. In some cases, to prevent hyperlipidemic pancreatitis, serum triglyceride should be lower than 500 mg/dl. We report two cases of acute pancreatitis caused by dyslipidemia.
  • Keywords: Acute pancreatitis; Dyslipidemia
  • 1. Yadav D, Pitchumoni CS. Issues in hyperlipidemic pancreatitis. J Clin Gastroenterol 2003;36:54-62.
  • 2. Kim BK, Kim J, Chang WC, Yoo KH, Shin YG, Chung CH. Recurrent acute pancreatitis in a patient with type iib hyperlipoproteinemia: a case report and review of the literature in Korea. Yonsei Med J 2006;47:144-147.
  • 3. Kim YJ, Kim HJ, Kim HC, Kim SJ, Park SH. A case of acute hyperlipidemic pancreatitis in a patient suspected of familial combined hyperlipidemia. Korean J Med 2005;69:197-201.
  • 4. Kim YK, Kim HJ, Kim BH, Chang YW, Chang R. A case of acute pancreatitis with secondary hyperlipidemia. Korean J Gastroenterol 1991;23:993-998.
  • 5. Cho CS, Lee SH, Hong YS, Park DJ, Kim HY. A case of chylomicronemia syndrome in systemic lupus erythematosus. Korean J Med 1993;45:659-663.
  • 6. Speck L. Fall von lipamia. Arch Verin Wissenschaftl Heilkunde 1865;1:232.
  • 7. Fortson MR, Freedman SN, Webster PD 3rd. Clinical asscessment of hyperlipidemic pancreatitis. Am J Gastroenterol 1995;90:2134-2139.
  • 8. Havel RJ. Pathogenesis, differentiation and management of hypertriglyvemia. Adv Intern Med 1969;15:117.
  • 9. Gan SI, Edwards AL, Symonds CJ, Beck PL. Hypertriglyceridemia-induced pancreatitis. World J Gastroenterol 2006;12:7197-7202.
  • 10. Lesser PB, Warshaw AL. Diagnosis of pancreatitis masked by hyperlipidemia. Ann Intern Med 1975;82:795-798.
  • 11. Kim JQ, Song JH. Lipids. The Korean Society for Laboratory Medicine. Laboratory Medicine 2001;3rd ed. Seoul, Korea Medicine. 65.
  • 12. Brunzell JD. Hyperytriglyceridemia. N Engl J Med 2007;357:1009-1017.
Fig. 1
(A) Case 1. Lipoprotein electrophoresis shows Fredrickson/WHO classification type IV pattern that is pre-beta fraction (VLDL) dominant pattern. (B) Case 2. Lipoprotein electrophoresis shows Fredrickson/WHO classification type III pattern that is between beta (LDL) and pre-beta (VLDL) fraction dominant, which makes it difficult to fractionate between beta (LDL) and pre-beta (VLDL).
emj-34-55-g001.jpg
Fig. 2
Abdominal CT Finding of Case 1. (A) Initial abdominal CT scan shows diffuse peripancreatic fatty infiltration. (B) 2 weeks later, abdominal CT scan shows a pseudocyst in infrapyloric area. but, decreased peripancreatic fatty infiltration. (C) 6 weeks later from initial abdominal CT, abdominal CT scan shows marked decreased pseudocyst in infrapyloric area. and, no visible peripancreatic fatty infiltration.
emj-34-55-g002.jpg
Fig. 3
Abdominal CT Finding of Case 2. Almost no enhancing viable pancreatic tissue in pancreatic tail portion with diffuse peripancreatic infiltration and fluid collection extended to perigastric are observed.
emj-34-55-g003.jpg

Figure & Data

References

    Citations

    Citations to this article as recorded by  

      Download Citation

      Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.

      Format:

      Include:

      Acute Pancreatitis Caused by Dyslipidemia
      Ewha Med J. 2011;34(2):55-59.   Published online September 30, 2011
      DOI: https://doi.org/10.12771/emj.2011.34.2.55
      Download Citation
      Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
      Format:
      • RIS — For EndNote, ProCite, RefWorks, and most other reference management software
      • BibTeX — For JabRef, BibDesk, and other BibTeX-specific software
      Include:
      • Citation for the content below
      Acute Pancreatitis Caused by Dyslipidemia
      Ewha Med J. 2011;34(2):55-59.   Published online September 30, 2011
      DOI: https://doi.org/10.12771/emj.2011.34.2.55
      Close

      Figure

      • 0
      • 1
      • 2
      Acute Pancreatitis Caused by Dyslipidemia
      Image Image Image
      Fig. 1 (A) Case 1. Lipoprotein electrophoresis shows Fredrickson/WHO classification type IV pattern that is pre-beta fraction (VLDL) dominant pattern. (B) Case 2. Lipoprotein electrophoresis shows Fredrickson/WHO classification type III pattern that is between beta (LDL) and pre-beta (VLDL) fraction dominant, which makes it difficult to fractionate between beta (LDL) and pre-beta (VLDL).
      Fig. 2 Abdominal CT Finding of Case 1. (A) Initial abdominal CT scan shows diffuse peripancreatic fatty infiltration. (B) 2 weeks later, abdominal CT scan shows a pseudocyst in infrapyloric area. but, decreased peripancreatic fatty infiltration. (C) 6 weeks later from initial abdominal CT, abdominal CT scan shows marked decreased pseudocyst in infrapyloric area. and, no visible peripancreatic fatty infiltration.
      Fig. 3 Abdominal CT Finding of Case 2. Almost no enhancing viable pancreatic tissue in pancreatic tail portion with diffuse peripancreatic infiltration and fluid collection extended to perigastric are observed.

      Fig. 1

      Fig. 2

      Fig. 3

      Acute Pancreatitis Caused by Dyslipidemia
      Ewha Med J : The Ewha Medical Journal

      ABOUT

      BROWSE ARTICLES 

      JOURNAL POLICIES

      FOR CONTRIBUTORS 

      © Ewha Womans University College of Medicine.
      TOP