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Original Article

Differences in Bacterial Species and Their Resistance Rates based on Sputum Cultures between Tertiary Hospitals and Smaller Medical Institutions

Tae Hyung Kim, Kyung Pyo Cho, Jae Sung Lee, Yong Moon Woo, Ji Seok Seong, Chang Suk Noh1
The Ewha Medical Journal 2013;36(2):126-131. Published online: September 26, 2013

Department of Internal Medicine, Seoul Red Cross Hospital, Seoul, Korea.

1Department of Internal Medicine, Seoul Seonam Hospital, Seoul, Korea.

Corresponding author: Chang Suk Noh. Department of Internal Medicine, Seoul Seonam Hospital, Sinjeongyipen1-ro, Yangcheon-gu, Seoul 158-070, Korea. Tel: 82-2-6300-7777, Fax: 82-2-6300-9009, 00021@eussh.org
• Received: May 1, 2013   • Accepted: June 27, 2013

Copyright © 2013. Ewha Womans University School of Medicine

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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  • Objectives
    Since the 1990s, drug-resistant bacteria have become common pathogens of hospital-acquired infections. In recent years, healthcare-associated infections have come to the fore, and it is reported that distribution rates of these bacteria are comparable to those of hospital-acquired infections. However, there have been few studies on differences in resistant bacteria depending on the size of hospitals. Thus, the authors studied differences in drug-resistant bacteria between a tertiary hospital and smaller medical institutions.
  • Methods
    We retrospectively analyzed the clinical findings and sputum culture results of patients transferred from tertiary hospitals (group A, n=74) and those transferred from smaller medical institutions (group B, n=65).
  • Results
    The number of patients with malignancy was higher in group A than in group B. The length of intensive care unit stay was longer in group A than in group B. Antibiotic therapy and mechanical ventilation were more frequently used in group A than in group B. There were no significant differences between the 2 groups in bacterial species (Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa) and their resistance rates to carbapenem, while there were significant differences between the 2 groups in the bacterial species (Acinetobacter baumannii) and its resistance rate to carbapenem.
  • Conclusion
    In this study, there were significant differences between the 2 groups in the bacterial species and resistance rates to carbapenem for A. baumannii infection unlike other bacterial infections. Further studies on risk factors and patient classification are needed to confirm our results.
  • Keywords: Acinetobacter baumannii; Carbapenem resistance; Healthcare-associated infection
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Table 1
Characteristics and clinical features of the subjects: tertiary hospitals versus smaller medical institutions

Values are presented as mean±SD or number (%). ECOG, Eastern Cooperative Oncology Group; ICU, intensive care unit.

emj-36-126-i001.jpg
Table 2
Differences in bacterial species and their resistance rates based on sputum cultures between tertiary hospitals and smaller medical institutions

*Multi-drug resistant pathogen include MRSA, ESBL E. coli, ESBL K. pneumoniae, CRPA, and CRAB. MRSA, methicillin resistant Staphylococcus aures; ESBL, extended-spectrum beta-lactamase; CRPA, carbapenem resistant Pseudomonas aeruginosae; CRAB, carbapenem resistant Acinetobacter baumannii.

emj-36-126-i002.jpg

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      Differences in Bacterial Species and Their Resistance Rates based on Sputum Cultures between Tertiary Hospitals and Smaller Medical Institutions
      Ewha Med J. 2013;36(2):126-131.   Published online September 26, 2013
      DOI: https://doi.org/10.12771/emj.2013.36.2.126
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      Download a citation file in RIS format that can be imported by all major citation management software, including EndNote, ProCite, RefWorks, and Reference Manager.
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      Differences in Bacterial Species and Their Resistance Rates based on Sputum Cultures between Tertiary Hospitals and Smaller Medical Institutions
      Ewha Med J. 2013;36(2):126-131.   Published online September 26, 2013
      DOI: https://doi.org/10.12771/emj.2013.36.2.126
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      Differences in Bacterial Species and Their Resistance Rates based on Sputum Cultures between Tertiary Hospitals and Smaller Medical Institutions
      Differences in Bacterial Species and Their Resistance Rates based on Sputum Cultures between Tertiary Hospitals and Smaller Medical Institutions

      Characteristics and clinical features of the subjects: tertiary hospitals versus smaller medical institutions

      Values are presented as mean±SD or number (%). ECOG, Eastern Cooperative Oncology Group; ICU, intensive care unit.

      Differences in bacterial species and their resistance rates based on sputum cultures between tertiary hospitals and smaller medical institutions

      *Multi-drug resistant pathogen include MRSA, ESBL E. coli, ESBL K. pneumoniae, CRPA, and CRAB. MRSA, methicillin resistant Staphylococcus aures; ESBL, extended-spectrum beta-lactamase; CRPA, carbapenem resistant Pseudomonas aeruginosae; CRAB, carbapenem resistant Acinetobacter baumannii.
      Table 1 Characteristics and clinical features of the subjects: tertiary hospitals versus smaller medical institutions

      Values are presented as mean±SD or number (%). ECOG, Eastern Cooperative Oncology Group; ICU, intensive care unit.

      Table 2 Differences in bacterial species and their resistance rates based on sputum cultures between tertiary hospitals and smaller medical institutions

      *Multi-drug resistant pathogen include MRSA, ESBL E. coli, ESBL K. pneumoniae, CRPA, and CRAB. MRSA, methicillin resistant Staphylococcus aures; ESBL, extended-spectrum beta-lactamase; CRPA, carbapenem resistant Pseudomonas aeruginosae; CRAB, carbapenem resistant Acinetobacter baumannii.

      Table 1

      Table 2

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