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Case Report

Night Blindness Induced by Long-term External Bile Drainage

The Ewha Medical Journal 2015;38(1):42-45. Published online: March 26, 2015

Department of Internal Medicine, Bundang Jesaeng Hospital, Seongnam, Korea.

Corresponding author: Sang Jong Park. Department of Internal Medicine, Bundang Jesaeng Hospital, 20 Seohyeon-ro, 180 beon-gil, Bundang-gu, Seongnam 463-774, Korea. Tel: 82-31-779-0207, Fax: 82-31-779-0929, elwind@daum.net
• Received: July 25, 2014   • Accepted: October 8, 2014

Copyright © 2015, The Ewha Medical Journal

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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  • Vitamin A deficiency can occur as a result of malnutrition, malabsorption, or poor vitamin metabolism due to liver disease and night blindness might develop as the first symptom. Although there have been foreign reports about night blindness due to vitamin A deficiency which was derived from liver cirrhosis, primary biliary cirrhosis, intestinal bypass surgery or bariatric operation, it is hard to find reports about night blindness after percutaneous transhepatic biliary drainage for external bile drainage. We report a case of night blindness derived from fat-soluble vitamin A deficiency developed after long-term (18 months) external bile drainage for benign biliary stricture occurred after left hepatic lobectomy and hepaticojejunostomy due to the Klatskin tumor (IIIb). Her night blindness and low serum retinol level (0.02 mg/L) was dramatically improved after vitamin A supplementation. We recommend lipid-soluble vitamin supplementation on the case of long-term external bile drainage.
  • 1. Braunstein A, Trief D, Wang NK, Chang S, Tsang SH. Vitamin A deficiency in New York City. Lancet 2010;376:267.
  • 2. Chae T, Foroozan R. Vitamin A deficiency in patients with a remote history of intestinal surgery. Br J Ophthalmol 2006;90:955-956.
  • 3. Slater GH, Ren CJ, Siegel N, Williams T, Barr D, Wolfe B, et al. Serum fat-soluble vitamin deficiency and abnormal calcium metabolism after malabsorptive bariatric surgery. J Gastrointest Surg 2004;8:48-55.
  • 4. Goodman DS. Vitamin A and retinoids in health and disease. N Engl J Med 1984;310:1023-1031.
  • 5. Mahmood K, Samo AH, Jairamani KL, Ali G, Talib A, Qazmi W. Serum retinol binding protein as an indicator of vitamin A status in cirrhotic patients with night blindness. Saudi J Gastroenterol 2008;14:7-11.
  • 6. Waqar S, Kersey T, Byles D. Night blindness in primary biliary cirrhosis. CMAJ 2010;182:1212.
  • 7. Phillips JR, Angulo P, Petterson T, Lindor KD. Fat-soluble vitamin levels in patients with primary biliary cirrhosis. Am J Gastroenterol 2001;96:2745-2750.
  • 8. Walt RP, Kemp CM, Lyness L, Bird AC, Sherlock S. Vitamin A treatment for night blindness in primary biliary cirrhosis. Br Med J (Clin Res Ed) 1984;288:1030-1031.
  • 9. Yoon DH, Lee SW, Choi U. Opthalmology; 7th ed. Seoul: Ilchokak; 2006.
  • 10. Smith J, Steinemann TL. Vitamin A deficiency and the eye. Int Ophthalmol Clin 2000;40:83-91.
Fig. 1

Magnetic resonance cholangiopancreatography 3 years after the operation. Severe stenosis is noticed at hepaticojejunostomy site (arrow).

emj-38-42-g001.jpg
Fig. 2

Percutaneous transhepatic biliary drainage is placed at the bile duct of posterior inferior segment (B6).

emj-38-42-g002.jpg
Fig. 3

Magnetic resonance cholangiopancreatograph (MRCP) 4 years after the operation. There is no change compared with the previous MRCP.

emj-38-42-g003.jpg

Figure & Data

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      Night Blindness Induced by Long-term External Bile Drainage
      Image Image Image
      Fig. 1 Magnetic resonance cholangiopancreatography 3 years after the operation. Severe stenosis is noticed at hepaticojejunostomy site (arrow).
      Fig. 2 Percutaneous transhepatic biliary drainage is placed at the bile duct of posterior inferior segment (B6).
      Fig. 3 Magnetic resonance cholangiopancreatograph (MRCP) 4 years after the operation. There is no change compared with the previous MRCP.
      Night Blindness Induced by Long-term External Bile Drainage
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