Abstract

• Lentiginosis profusa is characterized by the numerous dark brownish macules on whole body without anomalies of other organ and occurs from birth to early adulthood and has not family history. Two cases of lentiginosis profusa were confirmed by characteristic clinical and histopathological findings. On physical examination, they were well developed, chest roentgenogram and electrocardiogram were within normal limit. On histopathologic examination of dark brown macule showed a slight to moderate elongation of rete ridge and increase of both melanocyte number and melanin amount at basal cell layer.