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Review Article

Review of Injection Laryngoplasty as Treatment of Voice Disorders

Sung Min Chung, Han Su Kim, Hae Sang Park
The Ewha Medical Journal 2011;34(2):13-18. Published online: September 30, 2011

Division of Head & Neck Surgery, Department of Otorhinolaryngology, Ewha Womans University School of Medicine, Seoul, Korea

Corresponding author: Sung Min Chung, Tel: 02-2650-6163, Fax: 02-2648-5604 E-mail: sungmin@ewha.ac.kr

Copyright © 2011 Ewha Womans University School of Medicine

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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  • In the past decade, vocal fold injection (VFI) has re-emerged as a valuable treatment modality for a variety of laryngeal disorders. It offers many advantages for the treatment of glottal insufficiency. It can avoid surgical scar and is easily performed with local anesthesia. In this article, we describe the indication of injection laryngoplasty, variable injection materials and discuss about vocal fold injection approaches.
  • Keywords: Vocal fold injection; Injection laryngoplasty
Table 1.
Injectable materials
일시적 성대주입물질(Temporary injectable materials)
  Hyaluronic acid gel (RestylaneⓇ, HyalaformⓇ, RevidermⓇ, RofilanⓇ)
Collagen-based products (ZplastⓇ, CosmoplastⓇ, CosodermⓇ, CymetraⓇ, ShebaⓇ)
Carboxymethylcellulose (Radiesse voice gelⓇ)
Bovine gelatin (GelfoamⓇ, SurgifoamⓇ)
영구적 성대주입물질(Long term/Permanent injectable materials)
Calcium hydroxylapatitie (RadiesseⓇ)
Autologous fat
Polymethylmethacrylate (PMMA) microspheres suspended in a 3.5% bovine collagen solution (ArtecollⓇ)
Polyacrylamide hydrogel (AquamidⓇ)
  • 1. Brunings W. Uber eine neue Behandlungsmethode der Rekurrenslahmung. Ver Dtsch Laryngol 1911;18:93-151.
  • 2. Rosen CA, Statham MM. Vocal fold injection as a treatment for glottic insufficiency: pro. Arch Otolaryngol Head Neck Surg 2010;136:825-827.
  • 3. Mallur PS, Rosen CA. Vocal fold injection: review of indications, techniques, and materials for augmentation. Clin Exp Otorhinolaryngol 2010;3:177-182.
  • 4. Kwon TK. Injection laryngoplasty. Korean J Otolaryngol-Head Neck Surg 2006;49:768-780.
  • 5. Rosen CA. Phonosurgical vocal fold injection: procedures and materials. Otolaryngol Clin North Am 2000;33:1087-1096.
  • 6. Kwon TK, Buckmire R. Injection laryngoplasty for management of unilateral vocal fold paralysis. Curr Opin Otolaryngol Head Neck Surg 2004;12:538-542.
  • 7. Simpson CB, Amin MR. Office-based procedures for the voice. Ear Nose Throat J 2004;83:6-9.
  • 8. Schramm VL, May M, Lavorato AS. Gelfoam paste injection for vocal cord paralysis: temporary rehabilitation of glottic incompetence. Laryngoscope 1978;88:1268-1273.
  • 9. Shindo ML, Zaretsky LS, Rice DH. Autologous fat injection for unilateral vocal fold paralysis. Ann Otol Rhinol Laryngol 1996;105:602-606.
  • 10. Ford CN, Martin DW, Warner TF. Injectable collagen in laryngeal rehabilitation. Laryngoscope 1984;94:513-518.
  • 11. Remacle M, Lawson G. Results with collagen injection into the vocal folds for medialization. Curr Opin Otolaryngol Head Neck Surg 2007;15:148-152.
  • 12. Min JY, Hong SD, Kim K, Son YI. Long-term results of Artecoll injection laryngoplasty for patients with unilateral vocal fold motion impairment: safety and clinical efficacy. Arch Otolaryngol Head Neck Surg 2008;134:490-496.
  • 13. Lee NH, Jin SM. Office based injection laryngoplasty. J Korean Soc Logoped Phoniatr 2009;20:17-20.
  • 14. Park YH, Kim JH. Complication of injection laryngoplasty. J Korean Soc Logoped Phoniatr 2011;22:13-17.
  • 15. Kwon TK, Schimidt JG, Rosen CA. Preliminary results of clinical application with a new temporary vocal fold injection materials: Radiesse Lite. J Korean Soc Logoped Phoniatr 2004;15:87-91.

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    • Complications of Injection Laryngoplasty
      Dong-Hyun Kim, Wonjae Cha
      Korean Journal of Otorhinolaryngology-Head and Neck Surgery.2024; 67(5): 263.     CrossRef

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    Review of Injection Laryngoplasty as Treatment of Voice Disorders
    Ewha Med J. 2011;34(2):13-18.   Published online September 30, 2011
    DOI: https://doi.org/10.12771/emj.2011.34.2.13
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    Review of Injection Laryngoplasty as Treatment of Voice Disorders
    Ewha Med J. 2011;34(2):13-18.   Published online September 30, 2011
    DOI: https://doi.org/10.12771/emj.2011.34.2.13
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    Review of Injection Laryngoplasty as Treatment of Voice Disorders
    Review of Injection Laryngoplasty as Treatment of Voice Disorders
    일시적 성대주입물질(Temporary injectable materials)
      Hyaluronic acid gel (RestylaneⓇ, HyalaformⓇ, RevidermⓇ, RofilanⓇ)
    Collagen-based products (ZplastⓇ, CosmoplastⓇ, CosodermⓇ, CymetraⓇ, ShebaⓇ)
    Carboxymethylcellulose (Radiesse voice gelⓇ)
    Bovine gelatin (GelfoamⓇ, SurgifoamⓇ)
    영구적 성대주입물질(Long term/Permanent injectable materials)
    Calcium hydroxylapatitie (RadiesseⓇ)
    Autologous fat
    Polymethylmethacrylate (PMMA) microspheres suspended in a 3.5% bovine collagen solution (ArtecollⓇ)
    Polyacrylamide hydrogel (AquamidⓇ)
    Table 1. Injectable materials

    Table 1.

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