Abstract

• Infantile atopic dermatitis is a very common and well known disorder, but this is still a disease of fascination and frustration to medical practitioners and researchers. Thus, the auther observed clinically 362 cases of infantile atopic dermatitis and then reported the results and reviewed literature briefly. The results were summerized as follows: 1) Three to five months at onset was the age of 30.1% of the total patients. 2) In atopic history of the patient's family, atopic dermatitis was 61.9% and urticaria 58.0% respectively, and the father's family was mainly involved. 3) Other combined atopic history of patients were bronchial asthma(5.8%), urticaria(9.9%) and only 1.1% of the patients had two atopic diseases simultaneouly. 4) Initial skin lesions were facial eczema(97.2%), extensor eczema(88.7%). Epidermal stigmata other than eczema were dry skin (76.0%), and pityriasis simplex(58.0%). 5) In dermatological complications of infantile atopic dermatitis of our series, viral and bacterial infections were the most common. 6) Ocular stigmata were only seen in one case as a cataract, and compared with other report of the investigator, it was a most significant difference. 7) Exacerbating factors of seasonal variations in winter season were most common. Others were psychogenic stimuli, contactants, irritants, frequent bathing, dry and hot environment. Relieving factors were spring season, rest, avoidance of skin irritation, wet and cool environment. 8) Total serum protein and fractions were not changed significantly.