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The Effect of BHA and BHT on Mixed Function Oxygenase of Liver Tissue

Nak Eung Sung
The Ewha Medical Journal 1989;12(1):7-11. Published online: July 24, 2015

Department of Biochemistry, College of Medicine, Ewha Womans University, Korea.

Corresponding author: Nak Eung Sung. Department Biochemistry, College of Medicine, Ewha Womans University, Korea.

Copyright © 1989. Ewha Womans University School of Medicine

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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  • To evaluate the effect of BHA and BHT on liver tissue, BHA and BHT, 100mg and 200mg/kg B.W. respectively, were given to experimental animals for 4 months.
    Microsomal cytochrome P-450, cytochrome b5, cytochrome C reductase activity and lipid peroxidation of liver tissue of experimental animal were measured.
    The results were as follow ;
    1) Cytochrome P-450 increased significantly in experimental group given BHA but cytochrome b5 did not.
    2) Cytochrome oxidnse activity increased moderately in BHA group but decreased in BHT group. From these finding, it can be assumed, that BHA and BHT has no great effect on human tissue.

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    • Inhibition effect against elastase, collagenase, hyaluronidase and anti-oxidant activity of thinning Green ball apple
      Yu-Jin Go, Ye-Eun Kim, Hyun-Nam Kim, Eun-Ho Lee, Eun-Bi Cho, Akhmadjon Sultanov, Soon-Il Kwon, Young-Je Cho
      Journal of Applied Biological Chemistry.2020; 63(1): 43.     CrossRef

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    The Effect of BHA and BHT on Mixed Function Oxygenase of Liver Tissue
    Ihwa Ŭidae chi. 1989;12(1):7-11.   Published online July 24, 2015
    DOI: https://doi.org/10.12771/emj.1989.12.1.7
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    The Effect of BHA and BHT on Mixed Function Oxygenase of Liver Tissue
    Ihwa Ŭidae chi. 1989;12(1):7-11.   Published online July 24, 2015
    DOI: https://doi.org/10.12771/emj.1989.12.1.7
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    The Effect of BHA and BHT on Mixed Function Oxygenase of Liver Tissue
    The Effect of BHA and BHT on Mixed Function Oxygenase of Liver Tissue
    Ewha Med J : The Ewha Medical Journal

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